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Crosstalk between KRAS and miRNAs in pancreatic cancer: Opportunities for its diagnosis, prognosis and therapeutic intervention (Review). [PDF]
Aloliqi AA +4 more
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<i>GPR176</i> represses mitophagy to promote the progression of osteosarcoma by facilitating mTORC1 activity via PI3K-AKT pathway. [PDF]
Jiang J +6 more
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Phenformin-Induced Apoptosis: A Potential Mechanism for Cervical Cancer Cell Inhibition. [PDF]
Subaiea GM +10 more
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A recipe for chaos: Extrachromosomal DNA and the hallmarks of cancer. [PDF]
Wong IT +10 more
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G-Protein Oncogenes in Acromegaly
Hormone Research, 2008G-proteins belong to a family of proteins which share the common properties of GTP binding and hydrolysis. Heterotrimeric G-proteins are composed of α-, β- and γ-subunits. The α-subunit which differs from one G-protein to another contains the GDP/GTP binding site and has intrinsic GTPase activity. The receptor occupancy causes displacement of bound GDP
A, Spada, L, Vallar
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Oncogenic proteins as tumor antigens
Current Opinion in Immunology, 1996Human immune responses to oncogenic proteins have been reported and are continuing to be defined. Immunity to nonmutated overexpressed oncoproteins as well as to mutated or unique cancer-specific oncoproteins has been identified. Immune system based treatments targeting oncogenic proteins have shown therapeutic efficacy in animals models and are ...
M L, Disis, M A, Cheever
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The Multilayered Regulation of the Oncogenic Protein YY1
Critical Reviews™ in Oncogenesis, 2017The multifunctional protein Yin Yang 1 (YY1) plays critical roles in tumorigenesis. YY1 has been shown to be involved in the development, progression, resistance, and invasiveness of many types of cancers. Today, the value of YY1 as a prognostic marker and as a potential target in cancer therapy is being explored by multiple research groups around the ...
Raed, Rizkallah, Myra M, Hurt
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