Results 231 to 240 of about 384,141 (378)

What makes oncogenes mutually exclusive?

Small GTPases, 2017
J. Cisowski, M. Bergo
semanticscholar   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Oncostatin M induced by STAT5-activating oncogenes promotes disease progression in hematologic malignancies. [PDF]

Signal Transduct Target Ther
Rassner M, Müller TA, Crossley KA, Andrieux G, Schaberg S, Endres C, Jakob L, Poggio T, Köhler N, Kolter J, Müller-Newen G, Schönberger K, Cabezas-Wallscheid N, Gonzalez-Menendez I, Quintanilla-Martinez L, Zwick M, Ashok D, Hartmann TN, Groß O, Gorka O, Follo M, Illert AL, Boerries M, Zeiser R, Duyster J.   +24 more
europepmc   +1 more source

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

Nature, 2014
P. Northcott, Catherine Lee, T. Zichner, A. Stütz, S. Erkek, D. Kawauchi, D. Shih, V. Hovestadt, M. Zapatka, D. Sturm, David T. W. Jones, M. Kool, M. Remke, F. Cavalli, S. Zuyderduyn, Gary D Bader, S. Vandenberg, L. Esparza, M. Ryzhova, Wei Wang, A. Wittmann, S. Stark, Laura Sieber, H. Şeker-Cin, Linda Linke, Fabian Kratochwil, N. Jäger, I. Buchhalter, Charles D. Imbusch, Gideon Zipprich, Benjamin Raeder, Sabine Schmidt, N. Diessl, S. Wolf, S. Wiemann, B. Brors, C. Lawerenz, J. Eils, H. Warnatz, T. Risch, M. Yaspo, Ursula D. Weber, C. Bartholomae, C. Kalle, E. Turányi, P. Hauser, Emma Sandén, A. Darabi, P. Siesjö, J. Štěrba, K. Zitterbart, D. Sumerauer, P. Sluis, R. Versteeg, R. Volckmann, J. Koster, M. Schuhmann, M. Ebinger, H. Grimes, G. Robinson, A. Gajjar, M. Mynarek, K. Hoff, S. Rutkowski, T. Pietsch, W. Scheurlen, J. Felsberg, G. Reifenberger, A. Kulozik, A. Deimling, O. Witt, R. Eils, R. Gilbertson, A. Korshunov, Michael D. Taylor, P. Lichter, J. Korbel, R. Wechsler-Reya, S. Pfister   +78 more
semanticscholar   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

The role of extrachromosomal DNA in tumorigenesis and progression. [PDF]

Front Oncol
Ma X, Yu X, Wu C, Song L.
europepmc   +1 more source

MYC oncogenes and human neoplastic disease

Oncogene, 1999
C. Nesbit, J. Tersak, E. Prochownik
semanticscholar   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Oncovirus classification and insights into herpes simplex virus, Varicella-Zoster virus. [PDF]

Cancer Cell Int
Ghaemi A, Sadeh S.
europepmc   +1 more source

Identification and Validation of Oncogenes in Liver Cancer Using an Integrative Oncogenomic Approach

Cell, 2006
L. Zender, M. Spector, W. Xue, P. Flemming, C. Cordon-Cardo, J. Silke, S. Fan, J. Luk, M. Wigler, G. Hannon, D. Mu, R. Lucito, S. Powers, S. Lowe   +13 more
semanticscholar   +1 more source