Results 41 to 50 of about 237,469 (282)
Differentiated thyroid cancer: Growth factors, oncogenes and environmental influences [PDF]
Archive of Oncology, 2003 The present data of growth factors, oncogenes, tumor-suppressor-genes and environmental factors can be summarized in thus: thyrotropin, growth factors and other hormones do increase thyrocyte growth and specific mutations of growth factor receptors ...
Paunović Ivan R.
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Protein transduction: A novel tool for tissue regeneration [PDF]
, 2002 Tissue regeneration in humans is limited and excludes vitals organs like heart and brain. Transformation experiments with oncogenes like T antigen have shown that retrodifferentiation of the respective cells is possible but hard to control. To bypass the
Derer W. +4 more
core +1 more source
Change in Polycythemia Vera Treatment: Ropeginterferon Alfa-2b in Light of Current Trials
Turkish Journal of Hematology, 2023 Ropeginterferon alfa-2b (RopegIFN) enables effective cytoreduction in polycythemia vera (PV). Recent analyses suggest that long-term RopegIFN therapy fulfills treatment goals important to patients with PV including good quality of life, the slowing of ...
Heinz Gisslinger
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High MYC mRNA expression is more clinically relevant than MYC DNA amplification in triple-negative breast cancer [PDF]
, 2019 DNA abnormalities are used in inclusion criteria of clinical trials for treatments with specific targeted molecules. MYC is one of the most powerful oncogenes and is known to be associated with triple-negative breast cancer (TNBC).
Dasgupta, Subhamoy +6 more
core +2 more sources
Coagulation in Brain Tumors: Biological Basis and Clinical Implications
Frontiers in Neurology, 2019 Cancer patients commonly show abnormal laboratory coagulation tests, indicating a subclinical hypercoagulable condition that contribute to morbidity and mortality.
Chiara Mandoj, Luigi Tomao, Laura Conti
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TMEM Proteins in Cancer: A Review
Frontiers in Pharmacology, 2018 A transmembrane protein (TMEM) is a type of protein that spans biological membranes. Many of them extend through the lipid bilayer of the plasma membrane but others are located to the membrane of organelles.
Kathleen Schmit, Carine Michiels
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Frontiers in Oncology, 2022 The incidence and mortality of Prostate Cancer (PCa) worldwide correlate with age and bad dietary habits. Previously, we investigated the mRNA/miRNA role on PCa development and progression using high fat diet (HFD) fed mice.
Rocío Belén Duca +7 more
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Molecular Mechanisms Underlying Hepatocellular Carcinoma
Viruses, 2009 Hepatocarcinogenesis is a complex process that remains still partly understood. That might be explained by the multiplicity of etiologic factors, the genetic/epigenetic heterogeneity of tumors bulks and the ignorance of the liver cell types that give ...
Christian Trepo, Philippe Merle
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Emerging Biomarkers for Predicting Bladder Cancer Lymph Node Metastasis
Frontiers in Oncology, 2021 Bladder cancer is one of the leading causes of cancer deaths worldwide. Early detection of lymph node metastasis of bladder cancer is essential to improve patients’ prognosis and overall survival.
Chunyu Zhang +11 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source