Results 121 to 130 of about 7,402 (232)

Oncolytic mechanisms and immunotherapeutic potential of Newcastle disease virus in cancer therapy [PDF]

open access: yesarXiv
Newcastle Disease Virus (NDV), classified as Avian orthoavulavirus 1 (avian paramyxovirus type 1), is a promising oncolytic agent that selectively targets and destroys cancer cells while sparing normal tissues. Its oncoselectivity exploits cancer-specific defects in antiviral defenses, particularly impaired Type I interferon signaling, and dysregulated
arxiv  

Precise Scheduling of Chemotherapy Primes VEGF-producing Tumors for Successful Systemic Oncolytic Virotherapy [PDF]

open access: hybrid, 2011
Timothy Kottke   +13 more
openalex   +1 more source

Mutations in the Glycoprotein of Vesicular Stomatitis Virus Affect Cytopathogenicity: Potential for Oncolytic Virotherapy [PDF]

open access: bronze, 2011
Valérie Janelle   +4 more
openalex   +1 more source

Targeting pediatric cancer stem cells with oncolytic virotherapy [PDF]

open access: bronze, 2012
Gregory K. Friedman   +4 more
openalex   +1 more source

A hybrid discrete-continuum modelling approach for the interactions of the immune system with oncolytic viral infections [PDF]

open access: yesarXiv
Oncolytic virotherapy, utilizing genetically modified viruses to combat cancer and trigger anti-cancer immune responses, has garnered significant attention in recent years. In our previous work arXiv:2305.12386, we developed a stochastic agent-based model elucidating the spatial dynamics of infected and uninfected cells within solid tumours.
arxiv  

Modeling oncolytic virus therapy with distributed delay and non-local diffusion [PDF]

open access: yesarXiv
In the field of modeling the dynamics of oncolytic viruses, researchers often face the challenge of using specialized mathematical terms to explain uncertain biological phenomena. This paper introduces a basic framework for an oncolytic virus dynamics model with a general growth rate $\mathcal{F}$ and a general nonlinear incidence term $\mathcal{G ...
arxiv  

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