Annals of Hepatology, 2008 Current oncolytic virotherapy strategies are based in the accumulated understanding of the common molecular mechanisms displayed during cell transformation and viral infection, like cell cycle and apoptosis deregulations.
Daniel Cervantes-García; +3 more
doaj +4 more sources
Oncolytic virotherapy as immunotherapy
Science, 2021 Description Recognizing immune responses to oncolytic virotherapy opens the way for new combinations Oncolytic virus (OV) therapy is now something of a misnomer.
A. Melcher, K. Harrington, R. Vile
semanticscholar +3 more sources
An Unconventional Case Study of Neoadjuvant Oncolytic Virotherapy for Recurrent Breast Cancer. [PDF]
Vaccines (Basel)Intratumoural oncolytic virotherapy may have promise as a means to debulk and downstage inoperable tumours in preparation for successful surgery. Here, we describe the unique case of a 50-year-old self-experimenting female virologist with locally ...
Forčić D +8 more
europepmc +2 more sources
Advances in oncolytic virotherapy
Communications Medicine, 2022 Recent years have seen rapid advances in the preclinical development and clinical evaluation of oncolytic (cancer-lysing) virus-based therapies, and these are emerging as treatment modality for some cancers.
S. Russell +3 more
semanticscholar +4 more sources
Comparative safety and efficacy of oncolytic virotherapy for the treatment of individuals with malignancies: a systematic review, meta-analysis, and Bayesian network meta-analysisResearch in context [PDF]
EClinicalMedicineSummary: Background: Oncolytic virotherapy (OV) is an innovative immunotherapy strategy. A comprehensive understanding of oncolytic viruses is essential for advancing research and clinical practice.
Poyee Lau +4 more
doaj +2 more sources
Nature Biomedical Engineering, 2021 Non-invasive imaging methods for detecting intratumoural viral spread and host responses to oncolytic virotherapy are either slow, lack specificity or require the use of radioactive or metal-based contrast agents.
O. Perlman +9 more
semanticscholar +3 more sources
The Potential of Oncolytic Virotherapy in the Treatment of Head and Neck Cancer: A Comprehensive Review. [PDF]
Int J Mol SciHead and neck cancer (HNC) represents a challenging oncological entity with significant morbidity and mortality rates. Despite advances in conventional therapies, including surgery, chemotherapy, and radiation therapy, the overall survival rates for ...
Spirito F +10 more
europepmc +2 more sources
Oncolytic Virotherapy as Emerging Immunotherapeutic Modality: Potential of Parvovirus H-1 [PDF]
, 2014 Human tumors develop multiple strategies to evade recognition and efficient suppression by the immune system. Therefore, a variety of immunotherapeutic strategies have been developed to reactivate and reorganize the human immune system.
Bernd Heinrich +6 more
core +4 more sources
The 16th international oncolytic virotherapy conference: from in vitro to clinical studies, novel approaches in cancer therapy meeting report [PDF]
Frontiers in ImmunologyThe 16th International Oncolytic Virotherapy Conference, which was held in the vibrant city of Rotterdam, Netherlands, on 27-30th November 2024, featured a variety of novel strategies for improving oncolytic virus therapy.
Elena Ekrami +4 more
doaj +2 more sources
Oncolytic Virotherapy for Cancer: Clinical Experience [PDF]
Biomedicines, 2021 Oncolytic viruses are a new class of therapeutics which are largely in the experimental stage, with just one virus approved by the FDA thus far. While the concept of oncolytic virotherapy is not new, advancements in the fields of molecular biology and ...
S. Chaurasiya, Y. Fong, S. Warner
semanticscholar +4 more sources