Results 41 to 50 of about 2,796 (165)
Improving the therapeutic efficacy of oncolytic viruses for cancer: targeting macrophages
Journal of Translational Medicine, 2023 Oncolytic viruses (OVs) for cancer treatment are in a rapid stage of development, and the direct tumor lysis and activation of a comprehensive host immune response are irreplaceable advantages of cancer immunotherapy.
Zhen Shen +7 more
doaj +1 more source
Oncolytic Virus Immunotherapy [PDF]
, 2022 Dear Readers, Oncolytic Viruses (OV) are self-propagating agents that can selectively induce the lysis of cancer cells while sparing normal tissues. OV-mediated cancer cell death is often immunogenic and triggers robust anticancer immune responses and ...
core +1 more source
The Role of Neutrophils in Oncolytic Orf Virus-Mediated Cancer Immunotherapy
Cells, 2022 Neutrophils are innate leukocytes with diverse effector functions that allow them to respond to pathogens rapidly. Accumulating evidence has highlighted these cells’ complex roles in the host’s response to viral infections and tumor progression ...
Jessica A. Minott +5 more
doaj +1 more source
Tumor Restrictions to Oncolytic Virus
Biomedicines, 2014 Oncolytic virotherapy has advanced since the days of its conception but therapeutic efficacy in the clinics does not seem to reach the same level as in animal models.
Markus Vähä-Koskela, Ari Hinkkanen
doaj +1 more source
Oncolytic Virotherapy for Cancer: Clinical Experience [PDF]
, 2021 Oncolytic viruses are a new class of therapeutics which are largely in the experimental stage, with just one virus approved by the FDA thus far. While the concept of oncolytic virotherapy is not new, advancements in the fields of molecular biology and ...
Yuman Fong +2 more
core +1 more source
Oscillation thresholds via the novel MBR method with application to oncolytic virotherapy
Nonlinear Analysis, 2022 Oncolytic virotherapy is a therapy for the treatment of malignant tumours. In some undesirable cases, the injection of viral particles can lead to stationary oscillations, thus preventing the full destruction of the tumour mass.
Bruno Buonomo +2 more
doaj +1 more source
YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells [PDF]
, 2013 Background: The brain cancer stem cell (CSC) model describes a small subset of glioma cells as being responsible for tumor initiation, conferring therapy resistance and tumor recurrence.
Mittelbronn, Michel Guy André +19 more
core +1 more source
Oncolytic virotherapy and microenvironment in multiple myeloma [PDF]
, 2021 Multiple myeloma (MM) is a hematologic malignancy characterized by the accumulation of bone marrow (BM) clonal plasma cells, which are strictly dependent on the microenvironment.
Giuliani N. +7 more
core +1 more source
iNew Medicine, EarlyView.ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
Progress of oncolytic virotherapy for neuroblastoma
Frontiers in Pediatrics, 2022 As a neuroendocrine tumor derived from the neural crest, neuroblastoma (NB) is the most common extracranial solid tumor in children. The prognosis in patients with low- and intermediate-risk NB is favorable while that in high-risk patients is often detrimental.
Xiao-Tong Chen +7 more
openaire +3 more sources