Results 21 to 30 of about 28,421 (276)

Oncolytic virotherapy – Forging its place in the immunomodulatory paradigm for Multiple Myeloma

Cancer Treatment and Research Communications, 2021
The treatment focus for multiple myeloma (MM) has recently pivoted towards immune modulating strategies, with T-cell redirection therapies currently at the forefront of drug development.
Joselle Cook, MD, Aldo A. Acosta-Medina, MD, Kah Whye Peng, PhD, Martha Lacy, MD, Stephen Russell, MD, PhD   +4 more
doaj   +2 more sources

A mathematical model of oncolytic virotherapy with time delay

Mathematical Biosciences and Engineering, 2019
Oncolytic virotherapy is an emerging treatment modality which uses replication-competent viruses to destroy cancers without causing harm to normal tissues.
Zizi Wang, Zhiming Guo, Hal Smith
doaj   +2 more sources

Oncolytic Virotherapy in Glioma Tumors [PDF]

International Journal of Molecular Sciences, 2020
Glioma tumors are one of the most devastating cancer types. Glioblastoma is the most advanced stage with the worst prognosis. Current therapies are still unable to provide an effective cure. Recent advances in oncolytic immunotherapy have generated great expectations in the cancer therapy field. The use of oncolytic viruses (OVs) in cancer treatment is
Sergio Rius‐Rocabert, Noemí Garcia‐Romero, Antonia. García Fernández, Ángel Ayuso‐Sacido, Estanislao Nistal‐Villán   +4 more
openalex   +5 more sources

Editorial: Oncolytic virotherapy. [PDF]

Front Mol Biosci, 2023
Al-Shammari AM, Piccaluga PP.
europepmc   +4 more sources

Emerging delivery strategy for oncolytic virotherapy. [PDF]

Mol Ther Oncol
Zhu J, Ma J, Huang M, Deng H, Shi G.
europepmc   +2 more sources

Oncolytic virotherapy [PDF]

Nature Biotechnology, 2012
Oncolytic virotherapy is an emerging treatment modality that uses replication-competent viruses to destroy cancers. Recent advances include preclinical proof of feasibility for a single-shot virotherapy cure, identification of drugs that accelerate intratumoral virus propagation, strategies to maximize the immunotherapeutic action of oncolytic viruses ...
Russell, Stephen J, Peng, Kah-Whye, Bell, John C   +2 more
openaire   +3 more sources

Oncolytic virotherapy provides a potent therapy option for squamous bladder cancer. [PDF]

Sci Rep
Pannhausen J, Wirtz J, Mantwill K, Holm PS, Schwamborn K, Jonigk DD, Gschwend JE, Rose M, Gaisa NT, Nawroth R.   +9 more
europepmc   +3 more sources

Current strategies in engaging oncolytic viruses with antitumor immunity

Molecular Therapy: Oncolytics, 2021
Oncolytic virotherapy has produced promising yet limited results in preclinical and clinical studies. Besides direct oncolytic activity, a significant therapeutic mechanism of oncolytic virotherapy is the induction of tumor-specific immunity ...
Drew Ashton Boagni, Divya Ravirala, Shaun Xiaoliu Zhang   +2 more
doaj   +1 more source

Oncolytic virotherapy: basic principles, recent advances and future directions

Signal Transduction and Targeted Therapy, 2023
Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they are generally considered to have direct oncolysis and cancer immune effects.
Danni Lin, Yinan Shen, T. Liang
semanticscholar   +1 more source

Oncolytic viruses encoding bispecific T cell engagers: a blueprint for emerging immunovirotherapies

Journal of Hematology & Oncology, 2021
Bispecific T cell engagers (BiTEs) are an innovative class of immunotherapeutics that redirect T cells to tumor surface antigens. While efficacious against certain hematological malignancies, limited bioavailability and severe toxicities have so far ...
Johannes P. W. Heidbuechel, Christine E. Engeland   +1 more
doaj   +1 more source