Results 21 to 30 of about 7,402 (232)
On the Treatment of Melanoma: A Mathematical Model of Oncolytic Virotherapy [PDF]
, 2023 We develop and analyze a mathematical model of oncolytic virotherapy in the treatment of melanoma. We begin with a special, local case of the model, in which we consider the dynamics of the tumour cells in the presence of an oncolytic virus at the primary tumour site.
arxiv +1 more source
Oncolytic virotherapy for tumours following a Gompertz growth law [PDF]
Journal of Theoretical Biology 480:129-140 (2019), 2021 We present a mathematical model describing oncolytic virotherapy treatment of a tumour that proliferates according to a Gompertz growth function. We present local stability analysis and bifurcation plots for relevant model parameters to investigate the typical dynamical regimes that the model allows.
arxiv +1 more source
Oncolytic virotherapy and the current approaches in veterinary medicine
German Journal of Veterinary Research, 2022 Cancer has an increasing incidence worldwide in humans and animals. In addition to traditional treatments such as surgery, radiotherapy, and chemotherapy, there is a search for new treatment strategies for cancer treatment.
Bengu Bilgic, Banu Dokuzeylul, Mehmet Or
doaj +1 more source
On a three-dimensional and two four-dimensional oncolytic viro-therapy models [PDF]
Bol. Soc. Mat. Mex., 29, 63 (2023), 2022 We revisit here and carry out further works on tumor-virotherapy compartmental models of [Tian, 2011, Wang et al., 2013, Phan and Tian, 2017, Guo et al., 2019]. The results of these papers are only slightly pushed further. However, what is new is the fact that we make public our electronic notebooks, since we believe that easy electronic ...
arxiv +1 more source
Oncolytic virotherapy for ovarian cancer [PDF]
Oncolytic Virotherapy, 2012 In the past two decades, more than 20 viruses with selective tropism for tumor cells have been developed as oncolytic viruses (OVs) for treatments of a variety of malignancies. Of these viruses, eleven have been tested in human ovarian cancer models in preclinical studies.
Li, Shoudong +4 more
openaire +6 more sources
Agent-based and continuum models for spatial dynamics of infection by oncolytic viruses [PDF]
Bull Math Biol 85, 92 (2023), 2023 The use of oncolytic viruses as cancer treatment has received considerable attention in recent years, however the spatial dynamics of this viral infection is still poorly understood. We present here a stochastic agent-based model describing infected and uninfected cells for solid tumours, which interact with viruses in the absence of an immune response.
arxiv +1 more source
Implications of MicroRNAs in Oncolytic Virotherapy [PDF]
Frontiers in Oncology, 2017 MicroRNAs (miRNAs) are an abundant class of small non-coding RNA molecules (~22 nt) that can repress gene expression. Deregulation of certain miRNAs is widely recognized as a robust biomarker for many neoplasms, as well as an important player in tumorigenesis and the establishment of tumoral microenvironments.
Xavier Bofill-De Ros +5 more
openaire +4 more sources
Progress of oncolytic virotherapy for neuroblastoma
Frontiers in Pediatrics, 2022 As a neuroendocrine tumor derived from the neural crest, neuroblastoma (NB) is the most common extracranial solid tumor in children. The prognosis in patients with low- and intermediate-risk NB is favorable while that in high-risk patients is often detrimental.
Xiao-Tong Chen +7 more
openaire +3 more sources
A progressive stage IIIB melanoma treated with oncolytic ECHO-7 virus: A case report
SAGE Open Medical Case Reports, 2020 Melanoma is an aggressive skin cancer form with a grave prognosis. Current results suggest that oncolytic virus treatment of melanoma has a high therapeutic potential. ECHO-7 (Rigvir) is the first oncolytic virus registered in Latvia.
Vladimirs Sorokins +6 more
doaj +1 more source
Tropism and transduction of oncolytic adenovirus vectors in prostate cancer therapy
Frontiers in Bioscience-Landmark, 2021 Oncolytic adenovirus has been applied in cancer therapy because of several advantages such as cost-effective production, high transduction efficiency and low toxicity.
Chuang Wu +6 more
doaj +1 more source