Results 31 to 40 of about 28,421 (276)

Lung cancer and oncolytic virotherapy——enemy's enemy

Translational Oncology, 2023
Lung cancer is one of the malignant tumors that seriously threaten human health worldwide, while the covid-19 virus has become people's nightmare after the coronavirus pandemic. There are too many similarities between cancer cells and viruses, one of the
Zhang Li, Zhang Feiyue, Li Gaofeng, Liang Haifeng   +3 more
doaj   +1 more source

Induction of abscopal effect combining H101 oncolytic virotherapy with tislelizumab in a patient with advanced hepatocellular carcinoma: a case report. [PDF]

Am J Cancer Res
Ou D, Li Y, Wu J, Ou S, Xie F.
europepmc   +2 more sources

Oncolytic Virotherapy for Melanoma Brain Metastases, a Potential New Treatment Paradigm?

Brain Sciences, 2021
Introduction: Melanoma brain metastases remain a devastating disease process with poor prognosis. Recently, there has been a surge in studies demonstrating the efficacy of oncolytic virotherapy for brain tumor treatment.
Sauson Soldozy, Kathleen M. Mulligan, David X. Zheng, Melissa A. Levoska, Christopher R. Cullison, Turki Elarjani, Daniel G. Eichberg, Leonel E. Ampie, Ashish H. Shah, Kaan Yağmurlu, Mark E. Shaffrey, Jeffrey F. Scott, Ricardo J. Komotar   +12 more
doaj   +1 more source

Experimental Evolution of an Oncolytic Vesicular Stomatitis Virus with Increased Selectivity for p53-Deficient Cells [PDF]

, 2014
Experimental evolution has been used for various biotechnological applications including protein and microbial cell engineering, but less commonly in the field of oncolytic virotherapy.
A Buckling, A Takaoka, AT Da Poian, BD Lichty, BK Jha, BW Grinnell, C Muñoz-Fontela, Carmen Rivas, DF Stojdl, E Hastie, EJ Faul, F Le Boeuf, G Wollmann, G Wollmann, GJ Letchworth, I Kuhn, I Pagán, I Palmero, IP Greene, IS Novella, J Martínez-Picado, JD Walker, Jean-Simon Diallo, JF Heiber, JJ Bull, JM Cuevas, JM Cuevas, JS Diallo, K Rainwater-Lovett, L Marcos-Villar, L Wu, M Dragosits, Marta M. Alonso, MG Kurilla, O Ebert, P Agudelo-Romero, Pablo Hernández-Alonso, PE Turner, R Alemany, R Belshaw, R Miralles, R Sanjuán, R Sanjuán, RA Burrell, Rafael Sanjuán, Raquel Garijo, RD Socha, S Elena, S Roche, SF Elena, SJ Russell, SK Remold, SP Whelan, TG Uil, TS Miest, V Furió, V Janelle, W Yan, Y Gao, Z Zhang   +59 more
core   +12 more sources

IFNAR blockade synergizes with oncolytic VSV to prevent virus-mediated PD-L1 expression and promote antitumor T cell activity

Molecular Therapy: Oncolytics, 2022
Oncolytic virotherapies have shown excellent promise in a variety of cancers by promoting antitumor immunity. However, the effects of oncolytic virus-mediated type I interferon (IFN-I) production on antitumor immunity remain unclear.
Nader El-Sayes, Scott Walsh, Alyssa Vito, Amir Reihani, Kjetil Ask, Yonghong Wan, Karen Mossman   +6 more
doaj   +1 more source

Oncolytic virotherapy in cancer treatment: challenges and optimization prospects

Frontiers in Immunology, 2023
Oncolytic viruses (OVs) are emerging cancer therapeutics that offer a multifaceted therapeutic platform for the benefits of replicating and lysing tumor cells, being engineered to express transgenes, modulating the tumor microenvironment (TME), and ...
Lingjuan Chen, Mengsi Zuo, Qin Zhou, Yang Wang   +3 more
semanticscholar   +1 more source

Oncolytic Virotherapy Trials—Letter [PDF]

Clinical Cancer Research, 2013
We would like to thank Prof. Harrington for his insightful commentary ([1][1]) regarding our article by Kanerva and colleagues ([2][2]). During 2007–2011, the Advanced Therapy Access Program (ATAP) provided a unique opportunity for patients to access a technology they would not otherwise have ...
Hemminki Akseli, Oksanen Minna, Hemminki Akseli, Oksanen Minna   +3 more
openaire   +2 more sources

Optimizing Oncolytic Virotherapy for Malignant Glioma: From Bench to Bedside [PDF]

Cancer Manag Res
Jiang W, Tian Y, Gu H, Guan W.
europepmc   +3 more sources

Clinical Advances and Future Directions of Oncolytic Virotherapy for Head and Neck Cancer

Cancers, 2023
Simple Summary Head and neck cancer (HNC) is a significant global health issue, and traditional treatments such as surgery, chemotherapy, and radiation therapy often have limited success, especially in advanced cases. Oncolytic virotherapy (OVT) offers a
Zhan Wang, Peng Sun, Zhiyong Li, Shaowen Xiao   +3 more
semanticscholar   +1 more source

Modifying oncolytic virotherapy to overcome the barrier of the hypoxic tumor microenvironment. Where do we stand?

Cancer Cell International, 2022
Viruses are completely dependent on host cell machinery for their reproduction. As a result, factors that influence the state of cells, such as signaling pathways and gene expression, could determine the outcome of viral pathogenicity.
Sara Shayan, Arash Arashkia, Kayhan Azadmanesh   +2 more
doaj   +1 more source