Results 81 to 90 of about 21,338 (215)

Sorting out Pandora’s box: discerning the dynamic roles of liver microenvironment in oncolytic virus therapy for hepatocellular carcinoma

Frontiers in Oncology, 2014
Oncolytic viral therapies have recently found their way into clinical application for hepatocellular carcinoma (HCC), a disease with limited treatment options and poor prognosis. Adding to the many intrinsic challenges of in vivo oncolytic viral therapy,
Oliver eEbert, Jennifer eAltomonte
doaj   +1 more source

Recent Cutting‐Edge Technologies for the Delivery of Peptide Nucleic Acid

Chemistry – A European Journal, Volume 31, Issue 34, June 17, 2025.
This review provides an overview of PNA cellular delivery methods, starting with traditional peptide‐based systems and progressing to advanced approaches using nanoparticles, liposomes, and calixarene. It highlights how these innovative strategies have opened the way for more effective and efficient PNA delivery, ultimately enhancing the potential for ...
Concetta Avitabile, Maria Teresa Cerasa, Antonia D'Aniello, Michele Saviano, Maria Moccia   +4 more
wiley   +1 more source

Oncolytic vaccinia virus and cancer immunotherapy

Frontiers in Immunology
Oncolytic virotherapy (OVT) is a promising form of cancer treatment that uses genetically engineered viruses to replicate within cancer cells and trigger anti-tumor immune response. In addition to killing cancer cells, oncolytic viruses can also remodel the tumor microenvironment and stimulate a long-term anti-tumor immune response.
Lihua Xu, Huihui Sun, Nicholas R. Lemoine, Nicholas R. Lemoine, Yujing Xuan, Pengju Wang   +5 more
openaire   +3 more sources

Lung cancer and oncolytic virotherapy——enemy's enemy

Translational Oncology, 2023
Lung cancer is one of the malignant tumors that seriously threaten human health worldwide, while the covid-19 virus has become people's nightmare after the coronavirus pandemic. There are too many similarities between cancer cells and viruses, one of the
Zhang Li, Zhang Feiyue, Li Gaofeng, Liang Haifeng   +3 more
doaj  

Recombinant mumps virus as a cancer therapeutic agent

Molecular Therapy: Oncolytics, 2016
Mumps virus belongs to the family of Paramyxoviridae and has the potential to be an oncolytic agent. Mumps virus Urabe strain had been tested in the clinical setting as a treatment for human cancer four decades ago in Japan.
Arun Ammayappan, Stephen J Russell, Mark J Federspiel   +2 more
doaj   +1 more source

Virology: An Oncolytic Virus [PDF]

, 1971

openalex   +1 more source

Advances in cell-based delivery of oncolytic viruses as therapy for lung cancer

Molecular Therapy: Oncology
Lung cancer’s intractability is enhanced by its frequent resistance to (chemo)therapy and often high relapse rates that make it the leading cause of cancer death worldwide.
Giti Esmail Nia, Elahe Nikpayam, Molood Farrokhi, Azam Bolhassani, Ralph Meuwissen   +4 more
doaj  

A mathematical model of oncolytic virotherapy with time delay

Mathematical Biosciences and Engineering, 2019
Oncolytic virotherapy is an emerging treatment modality which uses replication-competent viruses to destroy cancers without causing harm to normal tissues.
Zizi Wang, Zhiming Guo, Hal Smith
doaj   +1 more source

Oncolytic therapy using a mutant type-1 herpes simplex virus and the role of the immune system [PDF]

, 1999
Eric S. Lambright, David Caparrelli, Abbas E. Abbas, T Toyoizumi, George Coukos, Katherine L. Molnar-Kimber, Larry R Kaiser   +6 more
openalex   +1 more source

A Novel Approach to Cancer Therapy Using an Oncolytic Herpes Virus to Package Amplicons Containing Cytokine Genes [PDF]

, 2001
John F. Carew, David A. Kooby, Marc W. Halterman, Se‐Heon Kim, Howard J. Federoff, Yuman Fong   +5 more
openalex   +1 more source