Results 151 to 160 of about 1,862,769 (263)
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins +3 more
wiley +1 more source
Advances in Oncolytic Viral Therapy in Melanoma: A Comprehensive Review
Checkpoint inhibitor therapy revolutionized the treatment of patients with melanoma. However, in patients where melanoma exhibits resistance to checkpoint inhibitor therapy, the treatment options are limited.
Ayushi Garg +12 more
doaj +1 more source
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Combination therapy with CAR T cells and oncolytic viruses: a new era in cancer immunotherapy
R. Rezaei +7 more
semanticscholar +1 more source
Oncolytic viruses cancer therapy [PDF]
Wild-type viruses with intrinsic oncolytic capacity in human includes DNA viruses like some autonomous parvoviruses and many RNA viruses. Recent advances in molecular biology have allowed the design of several genetically modified viruses, such as ...
Zeicher, Marc
core
Immune mediated and direct killing of colorectal cancer by reovirus [PDF]
Colorectal cancer remains the second most prevalent cancer in the world. Novel treatment strategies are necessary, especially for the treatment of metastatic disease.
Adair, Robert Allan
core
Oncolytic viruses as therapeutic agents
The concept of using viruses as oncolytic agents has a long history. However, relatively new developments are the use of these viruses as gene delivery vehicles and the restriction of viral replication and lysis to tumour cells. The latter is attempted by the use of tumour-specific promoters, which transcriptionally target viral genes involved in ...
openaire +2 more sources
Oncolytics, Cancer-Fighting Viruses from Past to Future: A Literature Review [PDF]
Background and Aim: Oncolytic viruses, as novel and advanced tools in the field of treating various types of cancer, have played a very important role in medical developments.
Seyedeh Nasim Mirbahari +4 more
doaj
The Potency of Mesenchymal Stem Cells as Viral Oncolytic Carriers
Oncolytic viruses (OVs) represent a category of viruses that selectively replicate within tumor cells, destroying cancer cells through a dual mechanism involving viral oncolysis and the stimulation of the host's anti-tumor immune response.
Muhammad Farid Rakhman
doaj +1 more source
Improved Oncolytic Viruses as Cancer Therapeutic agents : Issues and Solutions of Oncolytic Viruses [PDF]
P(論文)Anticancer agents used in cancer chemotherapy act on the cell division process and cause side effects that reduce the patient's quality of life. However, oncolytic viruses are cancer therapeutic agents with no side effects that are now attracting ...
永井, 勝幸 +12 more
core +1 more source

