Results 121 to 130 of about 21,326 (236)

Serielle Genexpressionsanalyse der Neointimabildung nach Ballonangioplastie im humanen Organkulturmodell mittels DNA Array-Technologie: Neue Erkenntnisse zur Wirkung von Rapamycin [PDF]

open access: yes, 2005
Hintergrund und Fragestellung Eines der schwerwiegenden Probleme der interventionellen Kardiologie stellte bislang die koronare Restenose im Stent dar.
Nührenberg, Thomas
core  

Elevation of Plasma Oncostatin M in Heart Failure

open access: yesFuture Cardiology, 2017
Oncostatin M (OSM) is an inflammatory cytokine of the gp130 family. OSM could participate in adverse cardiovascular remodeling through regulation of FGF23.OSM levels were determined in 80 heart failure patients with reduced left ventricular ejection fraction (HFrEF).OSM levels are significantly increased in HFrEF patients compared with healthy subjects.
Gruson, Damien   +3 more
openaire   +3 more sources

Comparison of Oncostatin M in Patients with Chronic Periodontitis with and without Diabetes

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022
Objective: To compare the Oncostatin M (OSM) concentrations in tissues of patients with chronic periodontitis with and without diabetes. Material and Methods: Sixty-four subjects visiting the dental outpatient department were categorized as “healthy ...
Amulya Kolluri   +4 more
doaj  

Oncostatin M reverses ABCG2-mediated mitoxantrone resistance

open access: yesBiomedicine & Pharmacotherapy
Mitoxantrone resistant variant of SW620 line was developed, characterized and subsequently used as a model system to determine oncostatin M ability to modulate MDR phenomenon. The selection regimen allowed for overexpression of ABCG2 and ABCB1 both at the RNA and protein level, which was further confirmed by functional assays.
Andrzej, Błauż   +2 more
openaire   +2 more sources

Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia

open access: yesCell & Bioscience
Background Primary cicatricial alopecia (PCA) causes irreversible hair loss due to immune-mediated hair follicle destruction. This study investigates follicle-targeted inflammation in lichen planopilaris (LPP), a major PCA subtype, to identify ...
Qitao Chen   +12 more
doaj   +1 more source

Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage [PDF]

open access: yesEuropean Cells & Materials, 2011
The relative contribution of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)4 and ADAMTS5 to aggrecan degradation under oncostatin M (OSM) stimulation, the role of the ancillary domains of the aggrecanases on their ability to ...
M Durigova   +4 more
doaj  

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