Results 101 to 110 of about 12,338 (205)

Inflammatory markers in prostate cancer: potential roles in risk stratification and immune profiling

Journal of Immunotoxicology
Inflammation plays a critical role in prostate cancer (PCa) pathophysiology, yet the diagnostic value of specific inflammatory markers remains unclear.
Edgaras Burzinskis, Ieva Janulaityte, Mindaugas Jievaltas, Darijus Skaudickas, Guoda Burzinskiene, Edvinas Dainius, Albinas Naudziunas, Astra Vitkauskiene   +7 more
doaj   +1 more source

Oncostatin M: Foe or friend? [PDF]

Arthritis & Rheumatism, 2003
Jean-Pierre, Pelletier, Johanne, Martel-Pelletier   +1 more
openaire   +2 more sources

Adipocyte Oncostatin Receptor Regulates Adipose Tissue Homeostasis and Inflammation

, 2020
Adipocytes are the largest cell type in terms of volume, but not number, in adipose tissue. Adipocytes are prominent contributors to systemic metabolic health.
Jacqueline M. Stephens, Sanchez-Infantes, David, David Sanchez-Infantes, Stephens, Jacqueline M   +3 more
core   +1 more source

Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage [PDF]

European Cells & Materials, 2011
The relative contribution of a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)4 and ADAMTS5 to aggrecan degradation under oncostatin M (OSM) stimulation, the role of the ancillary domains of the aggrecanases on their ability to ...
M Durigova, L Troeberg, H Nagase, PJ Roughley, JS Mort   +4 more
doaj  

Oncostatin M and Mechanotransduction in Bone Cells

, 2012
The study described herein investigated the relationship between Oncostatin M, the osteoblast cytoskeleton, and matrix compliance. Osteoblast cells are responsible for the formation of bone.
Mather, Kellen, Baker, Travis, Baughman, Nicholas   +2 more
core  

Single-cell sequencing combined with spatial transcriptomics reveals the characteristics of follicle-targeted inflammation patterns in primary cicatricial alopecia

Cell & Bioscience
Background Primary cicatricial alopecia (PCA) causes irreversible hair loss due to immune-mediated hair follicle destruction. This study investigates follicle-targeted inflammation in lichen planopilaris (LPP), a major PCA subtype, to identify ...
Qitao Chen, Yuqian Li, Qilin Zhu, Zhongming Li, Guanghui Shao, Yanjun Liu, Peixuan Jiang, Qiuwei Tao, Lili Shen, Jing Zhu, Linwei Wei, Yanhua Li, Xufeng Du   +12 more
doaj   +1 more source

Adipose Tissue Dysfunction Occurs Independently of Obesity in Adipocyte‐Specific Oncostatin Receptor Knockout Mice

, 2018
© 2018 The Obesity Society Objective: This study examined the phenotypic effects of adipocyte-specific oncostatin M receptor (OSMR) loss in chow-fed mice.
Carrie M. Elks, Elks, Carrie M., Dietrich, Marilyn A., Hardy Hang, Rittell, Victoria, Jacqueline M. Stephens, Randall L. Mynatt, Hang, Hardy, Victoria Rittell, Bailey, Jennifer L., Stephens, Jacqueline M., Jennifer L. Bailey, Marilyn A. Dietrich, Mynatt, Randall L.   +13 more
core   +1 more source

Die Wirkung von Oncostatin M und Ciliary Neurotrophic Factor auf das angiogene Verhalten von vaskulären Endothelzellen

Vasoproliferative Netzhauterkrankungen stellen eine Hauptursache für Erblindungen in der westlichen Welt dar. Chronische Entzündungsprozesse, unter anderem vermittelt durch Zytokine der IL-6 Familie, tragen zur Entstehung und Progression dieser ...
Rapp, Julian
core   +1 more source

Molekulare Mechanismen der Oncostatin M-vermittelten Signaltransduktion und deren Bedeutung in der Entzündung sowie der antiviralen Immunabwehr [PDF]

, 2009
Die Dissertation beschäftigt sich mit der Oncostatin M-vermittelten Signaltransduktion und dessen Bedeutung für den entzündlichen Verlauf einer Rheumatoiden Arthritis, die immunmodulatorischen Fähigkeiten von Tumoren sowie die antivirale ...
Hintzen, Christoph
core  

Suppression of gp130 attenuated insulin-mediated signaling and glucose uptake in skeletal muscle cells

Scientific Reports
The aim of the present study was to investigate the effects of Oncostatin M receptor (OSMR) subunit gp130 knockdown on insulin-stimulated glucose metabolism-related signaling pathways and glucose uptake in skeletal muscle cells.
Koji Sato
doaj   +1 more source