Results 81 to 90 of about 12,338 (205)

IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M

Mediators of Inflammation, 2020
The interleukin-1 family member IL-33 participates in both innate and adaptive T helper-2 immune cell responses in models of lung disease. The IL-6-type cytokine Oncostatin M (OSM) elevates lung inflammation, Th2-skewed cytokines, alternatively activated
Fernando Botelho, Anisha Dubey, Ehab A. Ayaub, Rex Park, Ashley Yip, Allison Humbles, Roland Kolbeck, Carl D. Richards   +7 more
doaj   +1 more source

Integrating Radiomics and Computational Pathology to Predict Early Recurrence of Pancreatic Ductal Adenocarcinoma and Uncover Its Biological Basis in Tumor Microenvironment

Advanced Science, Volume 13, Issue 32, 9 June 2026.
Accurate prediction of early recurrence in pancreatic ductal adenocarcinoma is vital for optimizing treatment. A novel, integrated radiomics‐pathology machine learning model successfully forecasts recurrence risks by analyzing preoperative CT images and computational pathology.
Sihang Cheng, Fuze Cong, Shenbo Zhang, Rui Lv, Wenjia Zhang, Xinyi Ke, Juncheng Wu, Zhonghe Zhao, Kui Zhao, Di Dong, Ruofan Zhang, Zhengyu Jin, Max Seidensticker, Zhiwei Wang, Huanwen Wu, Xianlin Han, Nan Hong, Huadan Xue   +17 more
wiley   +1 more source

Mouse Oncostatin M Transgene Construction

, 2000
Oncostatin M (OSM) was initially identified as a 28KD polypeptide cytokine which has been shown to inhibit the in vitro growth of cells from melanoma and other solid tumors, such as breast, ovarian, lung, cerebral meningioma, as well as normal and ...
Zhang, Yumei Lynda
core  

A Novel Missense Mutation in Oncostatin M Receptor Beta Causing Primary Localized Cutaneous Amyloidosis [PDF]

, 2014
Primary localized cutaneous amyloidosis (PLCA) is a chronic skin disorder, caused by amyloid material deposition in the upper dermis. Autosomal dominant PLCA has been mapped earlier to pathogenic missense mutations in the OSMR gene, which encodes the ...
Ebrahim-Habibi, Azadeh, Amoli, Mahsa M., Zarrabi, Fariba, Haghighi, Alireza, Saeedi, Marjan, Robati, Reza M.   +5 more
core   +1 more source

Proinflammatory biomarkers and platelet aggregation activity in patients with coronary artery disease

Бюллетень сибирской медицины
Aim. To determine concentrations and identify the relationship of biomarkers (endocan / cell-specific molecule-1, fatty acid binding protein 4 (FABP 4), placental growth factor (PlGF), oncostatin M), with parameters of collageninduced platelet ...
O. A. Trubacheva, I. V. Kologrivova, O. L. Schnaider, I. V. Petrova, V. N. Vasiliev, I. V. Kovalev, I. Yu. Yakimovich   +6 more
doaj   +1 more source

Combined Use of Fecal Biomarkers in Inflammatory Bowel Diseases: Oncostatin M and Calprotectin

Journal of Inflammation Research, 2021
Ying Cao,1,* Yibei Dai,1,* Lingyu Zhang,1 Danhua Wang,1 Wen Hu,2 Qiao Yu,3 Xuchu Wang,1 Pan Yu,1 Weiwei Liu,1 Ying Ping,1 Tao Sun,1 Yiwen Sang,1 Zhenping Liu,4 Yan Chen,3 Zhihua Tao1 1Department of Laboratory Medicine, Zhejiang University School ...
Cao Y, Dai Y, Zhang L, Wang D, Hu W, Yu Q, Wang X, Yu P, Liu W, Ping Y, Sun T, Sang Y, Liu Z, Chen Y, Tao Z   +14 more
doaj  

Oncostatin M, Interleukin-6, glucometabolic parameters and lipid profile in hypertensive patients with prediabetes and type 2 diabetes mellitus

, 2017
Background and aims: Essential hypertension and type 2 diabetes mellitus possess some common pathogenetic components, in particular, activation of immune inflammatory response, the intercellular mediators of which are cytokines.
Герасимчук, Нина Миколаївна, Демиденко, Ганна Валеріївна, Демиденко, Анна Валерьевна, Ashcheulova, Tetyana, Ащеулова, Татьяна Вадимовна, Gerasimchuk, Nina, Demydenko, Ganna, Кочубей, Оксана Анатольевна, Герасимчук, Нина Николаевна, Ащеулова, Тетяна Вадимівна, Кочубєй, Оксана Анатоліївна, Maliy, Alla, Kochubiei, Oksana   +12 more
core   +2 more sources

Indicators of endocrine function of muscle and fat tissue in athletes participating in martial arts

Спортивная медицина: наука и практика
Purpose of the study: the aim of that study was an investigation of the level of adipokines, myokines and growth factors in the blood of athletes involved in acyclic sports — martial arts.Materials and methods: we have investigated 15 male athletes aged ...
A. V. Shestopalov, V. V. Davydov, K. P. Merkel, T. V. Grigoryeva, D. S. Martykanova, N. Сh. Davletova, A. V. Laikov, S. A. Roumiantsev   +7 more
doaj   +1 more source

Integrative genomic and functional characterization of ADAMTS3 reveals its inflammatory regulation via NF‐κB and STAT3 pathways in osteosarcoma

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract Osteosarcoma (OS) is an aggressive bone malignancy characterized by genomic instability and extensive extracellular matrix (ECM) remodeling. Members of the ADAMTS family are matrix‐associated proteases implicated in tumorigenesis; however, their roles in OS remain poorly defined. This study provides a comprehensive genomic, transcriptomic, and
Ehed Muhammed Aymaz, Meltem Alper, Feyza Nur Sav, Tuğşen Aydemir, Feray Köçkar   +4 more
wiley   +1 more source

Harnessing energy metabolism for enhanced bone defect repair: Mechanisms and therapeutic strategies

VIEW, Volume 7, Issue 3, June 2026.
This review addresses the critical challenge of bone defect repair by focusing on the underexplored role of cellular energy metabolism. It synthesizes regulatory mechanisms in bone‐forming cells and sums up innovative strategies—leveraging cell derivatives, active factors, and biomimetic scaffolds—to modulate metabolism for enhanced regeneration.
Junting Li, Yulan Liu, Yuran Li, Yingjie Hua, Xinquan Jiang, Mingliang Zhou   +5 more
wiley   +1 more source