Results 91 to 100 of about 12,338 (205)
Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.ABSTRACT Tumour heterogeneity is a key factor in cancer progression, with immune responses within the tumour microenvironment (TME) contributing significantly to treatment resistance and immunotherapy outcomes. Recent advances in single‐cell RNA sequencing (scRNA‐seq) have provided unprecedented insights into the diverse immune cell populations ...
Sihan Chen +5 more
wiley +1 more source
Evaluation of Serum Oncostatin M in Inflammatory Bowel Disease Patients.
Minia Journal of Medical ResearchBackground: The exact etiology of IBD remains unclear, but it is believed to involve a complex interaction between genetic susceptibility, environmental factors, the intestinal microbiota and immune dysregulation. Oncostatin M is an emerging biomarker of
Asmaa Mehany +3 more
doaj +1 more source
Oncostatin M, an Underestimated Player in the Central Nervous System
Frontiers in Immunology, 2019 For a long time, the central nervous system (CNS) was believed to be an immune privileged organ. In the last decades, it became apparent that the immune system interacts with the CNS not only in pathological, but also in homeostatic situations. It is now
Evelien Houben +2 more
doaj +1 more source
, 1999 Oncostatin M (OM) is a member of the interleukin-6 (IL-6) cytokine subfamily. The binding of OM to its receptor initiates signal transduction through JAK-signal transducers and activators of transcription (STAT) pathways and activates transcription ...
core
Characterization of a gp130 Signaling Receptor Polymorphism [PDF]
, 2013 We previously reported an association between human herpesvirus 8 (HHV-8) seroprevalence and increased prostate cancer risk among men on the Caribbean island of Tobago.
Kercher, Katherine
core
Modulation der Hypophysen-Nebennierenrinde und Induktion von Apoptose an der adrenocorticalen Tumorzelle durch Oncostatin M [PDF]
, 2005 Diese Arbeit konnte Oncostatin M als Modulator der Hypothalamus-Hypophysen-Nebennierenrinden-Achse näher charakterisieren. Es konnte gezeigt werden, dass Oncostatin M an hypophysärem Gewebe über den gp130/LIFR-Komplex zur Aktivierung der Jak-STAT-Kaskade
Dorn, Franziska
core
Oncostatin M-induced genes in human astrocytomas
International Journal of Oncology, 2007 Oncostatin M (OSM) is a member of the interleukin-6 (IL-6) cytokine family and known to be induced in the nervous system as a result of cell stress. OSM is expressed in most human brain tumors, but the effects on tumor cells are unclear. The cytokine is known to activate the JAK/STAT signaling pathway by binding to its receptors gp130/OSMbeta or gp130 ...
Annika, Krona +3 more
openaire +3 more sources
Oncostatin M Is a Growth Factor for Ewing Sarcoma
The American Journal of Pathology, 2012 Primary bone tumors, osteosarcomas and chondrosarcomas, derive from mesenchymal stem cells committed into osteoblasts and chondrocytes; in Ewing sarcomas (ESs), the oncogenic fusion protein EWS-FLI1 prevents mesenchymal differentiation and induces neuroectodermic features.
David, Emmanuelle +9 more
openaire +5 more sources
Comparison of Oncostatin M in Patients with Chronic Periodontitis with and without Diabetes
Pesquisa Brasileira em Odontopediatria e Clínica Integrada, 2022 Objective: To compare the Oncostatin M (OSM) concentrations in tissues of patients with chronic periodontitis with and without diabetes. Material and Methods: Sixty-four subjects visiting the dental outpatient department were categorized as “healthy ...
Amulya Kolluri +4 more
doaj
Background: The use of high-sensitivity troponin levels increases the sensitivity of the diagnosis of non-ST elevation myocardial infarction (NSTEMI).
Özcan, M. +7 more
core +1 more source