Results 51 to 60 of about 56,604 (307)

Finite Analytic Method for One-Dimensional Nonlinear Consolidation under Time-Dependent Loading

open access: yesShock and Vibration, 2017
For one-dimensional (1D) nonlinear consolidation, the governing partial differential equation is nonlinear. This paper develops the finite analytic method (FAM) to simulate 1D nonlinear consolidation under different time-dependent loading and initial ...
Dawei Cheng   +3 more
doaj   +1 more source

One-Dimensional Consolidation Affected by Side Friction

open access: yesSoils and Foundations, 1969
SUMMARY This paper deals with the theoretical part of the investigations of the effect of side friction on the process of the one-dimensional consolidation. On the basis of the characteristics of the frictional resistance and the compressibility of soils, three kinds of fundamental equations are derived and numerically solved. From the view point of
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

One-dimensional consolidation of fractional order derivative viscoelastic saturated soils under arbitrary loading

open access: yesYantu gongcheng xuebao, 2017
The theory of fractional calculus is introduced into the Kelvin-Voigt constitutive model to describe the mechanical behavior of viscoelastic saturated soils.
WANG Lei 1,2, SUN De-an 1, XIE Yi 3, LI Pei-chao 3
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Analytical solution of one-dimensional electroosmotic consolidation considering the thermal effect

open access: yesShuiwen dizhi gongcheng dizhi
In recent years, electro-osmotic method is an effective foundation treatment method for dredged silt; however, few studies have focused on the influence of temperature on the electro-osmotic consolidation. To explore the influence of temperature field on
Qi LU, Ganbin LIU, Yongzheng MA
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Study on Micro-Structure of Loess under one-Dimensional Consolidation

open access: yes, 2011
The SEM images were obtained from three different sections of the specimens which suffered to one-dimensional consolidation under 5 grade pressures. Basic micro-structure parameters were obtained from these SEM images and their relations with various ...
Qing Yang, Ling Xia Gao, Mao Tian Luan
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Investigation of the Effects of Anisotropic Flow of Pore Water and Multilayered Soils on Three-Dimensional Consolidation Characteristics

open access: yesAdvances in Materials Science and Engineering, 2017
Many practical engineering problems are seriously different from the assumptions which are considered for one-dimensional consolidation test and need to concentrate on three-dimensional consolidation of soil under different boundary conditions.
Arpan Laskar, Sujit Kumar Pal
doaj   +1 more source

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