Results 101 to 110 of about 223,364 (391)

Combining data on the bioavailability of midazolam and physiologically‐based pharmacokinetic modeling to investigate intestinal CYP3A4 ontogeny

open access: yesCPT: Pharmacometrics & Systems Pharmacology
Pediatric physiologically‐based modeling in drug development has grown in the past decade and optimizing the underlying systems parameters is important in relation to overall performance.
Trevor N. Johnson   +4 more
doaj   +1 more source

Transcriptional Regulation of the Immune Receptor FLS2 Controls the Ontogeny of Plant Innate Immunity

open access: yesThe Plant Cell, 2018
miR172b regulates the transcription of FLS2 through TARGET OF EAT1 (TOE1) and TOE2, which governs the ontogeny of plant innate immunity. Innate immunity plays a vital role in protecting plants and animals from pathogen infections.
Yanmin Zou   +8 more
semanticscholar   +1 more source

Influence of Temperature, Hypercapnia, and Development on the Relative Expression of Different Hemocyanin Isoforms in the Common Cuttlefish Sepia officinalis [PDF]

open access: yes, 2012
The cuttlefish Sepia officinalis expresses several hemocyanin isoforms with potentially different pH optima, indicating their reliance on efficient pH regulation in the blood.
Gutowska, Magdalena A.   +7 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Leaf senescence of common bean plants as affected by soil phosphorus supply Senescência foliar do feijoeiro afetada pelo suprimento de fósforo no solo

open access: yesRevista Brasileira de Ciência do Solo, 2007
Responses of leaf senescence to P supply could constitute adaptive mechanisms for plant growth under P-limiting conditions. The aim of this study was to evaluate the effects of soil P supply on leaf senescence of common bean (Phaseolus vulgaris L ...
Adelson Paulo Araújo   +2 more
doaj   +1 more source

Living Close to Your Neighbors: The Importance of Both Competition and Facilitation in Plant Communities [PDF]

open access: yes, 2014
Recent work has demonstrated that competition and facilitation likely operate jointly in plant communities, but teasing out the relative role of each has proven difficult.
Reich, Peter B.   +2 more
core   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

The first report of South American edrioasteroids and the paleoecology and ontogeny of rhenopyrgid echinoderms [PDF]

open access: yes, 2013
A new species of rhenopyrgid edrioasteroid Rhenopyrgus piojoensis sp. nov. is described form the Silurian (Lower Lud− low) Los Espejos Formation in the Precordillera of Argentina.
Heredia, Susana Emma   +3 more
core   +1 more source

Craniofacial ontogeny in Tylosaurinae

open access: yesPeerJ, 2020
Mosasaurs were large, globally distributed aquatic lizards that lived during the Late Cretaceous. Despite numerous specimens of varying maturity, a detailed growth series has not been proposed for any mosasaur taxon. Two taxa—Tylosaurus prorigerandT. kansasensis/nepaeolicus—have robust fossil records with specimens spanning a wide range of sizes and ...
openaire   +4 more sources

Ontogeny of tubulointerstitial cells

open access: yesKidney International, 1991
In most parts of the kidney, interstitial cells surround the epithelial sheets. An exception is seen in the glomerulus, where instead endothelial cells face the glomerular epithelial cells. Although the interstitial cells are found around all tubular segments of the nephron, very little attention is usually paid to these cells in physiological or ...
Andreas Weller, Peter Ekblom
openaire   +3 more sources

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