Results 21 to 30 of about 269,389 (244)

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

PLoS Genetics, 2018
The N6-methyladenosine (m6A) modification is the most prevalent internal RNA modification in eukaryotes. The majority of m6A sites are found in the last exon and 3’ UTRs.
Seth D. Kasowitz, Jun Ma, S. Anderson, N. Leu, Yang Xu, B. Gregory, R. Schultz, R. Schultz, P. Wang   +8 more
semanticscholar   +1 more source

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm−oocyte fusion in mice

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance The sperm−oocyte fusion step is important to transport the male genome into oocytes. So far, IZUMO1 and FIMP have been identified as fusion-related proteins in spermatozoa, but the molecular mechanisms underpinning sperm−oocyte fusion and ...
Taichi Noda, Yonggang Lu, Yoshitaka Fujihara, Seiya Oura, Takayuki Koyano, Sumire V. Kobayashi, M. Matzuk, M. Ikawa   +7 more
semanticscholar   +1 more source

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

Nature Communications, 2018
Female meiotic divisions are asymmetric with the formation of large oocytes and small polar bodies, thought to result from cortical spindle placement before anaphase.
Zhe Wei, Jessica Greaney, Chenxi Zhou, Hayden A. Homer   +3 more
doaj   +1 more source

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Nature, 2017
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the ...
Ilya M. Flyamer, Johanna Gassler, Maxim Imakaev, Hugo B. Brandão, S. Ulianov, Nezar Abdennur, S. Razin, L. Mirny, Kikuë Tachibana-Konwalski   +8 more
semanticscholar   +1 more source

The influence of timing of oocytes retrieval and embryo transfer on the IVF-ET outcomes in patients having bilateral salpingectomy due to bilateral hydrosalpinx

Frontiers in Surgery, 2023
ObjectiveThe objective of the study was to investigate whether the sequence of oocyte retrieval and salpingectomy for hydrosalpinx affects pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET) patients.Study DesignThere were 1,610 ...
He Yilei, He Yilei, He Yilei, He Yilei, Yang Shuo, Yang Shuo, Yang Shuo, Yang Shuo, Ma Caihong, Ma Caihong, Ma Caihong, Ma Caihong, Yang Yan, Yang Yan, Yang Yan, Yang Yan, Song Xueling, Song Xueling, Song Xueling, Song Xueling, Zhang Jiajia, Zhang Jiajia, Zhang Jiajia, Zhang Jiajia, Liu Ping, Liu Ping, Liu Ping, Liu Ping, Li Rong, Li Rong, Li Rong, Li Rong, Qiao Jie, Qiao Jie, Qiao Jie, Qiao Jie   +35 more
doaj   +1 more source

Histology of the oocytes of Lutjanus peru (Nichols and Murphy, 1922) (Pisces: Lutjanidae)

Ciencias Marinas, 2001
The distinctive characteristics found in each of the development stages of the oocyte in the ovary of Lutjanus peru (Pacific red snapper) are described.
G Lucano-Ramírez, M Villagrán-SantaCruz, S Ruiz-Ramírez, T López-Murillo   +3 more
doaj   +1 more source

Impact of Maternal Age on Oocyte and Embryo Competence

Frontiers in Endocrinology, 2018
The overall success of human reproduction, either spontaneously or after IVF, is highly dependent upon maternal age. The main reasons for age-related infertility include reduced ovarian reserve and decreased oocyte/embryo competence due to aging insults,
D. Cimadomo, G. Fabozzi, A. Vaiarelli, N. Ubaldi, F. Ubaldi, L. Rienzi   +5 more
semanticscholar   +1 more source

The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

Cell Reports, 2022
Summary: Inactivation of cyclin-dependent kinase 1 (Cdk1), controlled by cyclin B1 proteolysis, orders events during mitotic exit. Here, we used a FRET biosensor to study Cdk1 activity while simultaneously monitoring anaphase II and pronuclear (PN ...
Chenxi Zhou, Hayden A. Homer
doaj  

Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance

Human Reproduction Update, 2016
BACKGROUND Successful cryopreservation of oocytes and embryos is essential not only to maximize the safety and efficacy of ovarian stimulation cycles in an IVF treatment, but also to enable fertility preservation.
L. Rienzi, C. Gracia, R. Maggiulli, A. Labarbera, D. Kaser, F. Ubaldi, S. Vanderpoel, C. Racowsky   +7 more
semanticscholar   +1 more source

Impact of Oxidative Stress on Age-Associated Decline in Oocyte Developmental Competence

Frontiers in Endocrinology, 2019
Reproductive capacity in women starts to decline beyond their mid-30s and pregnancies in older women result in higher rates of miscarriage with aneuploidy.
Hiroyuki Sasaki, T. Hamatani, Shintaro Kamijo, Maki Iwai, Masato Kobanawa, Seiji Ogawa, K. Miyado, Mamoru Tanaka   +7 more
semanticscholar   +1 more source