Results 21 to 30 of about 241,792 (308)

Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

Nature Communications, 2020
Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase
Zhe Wei, Jessica Greaney, Wei-Guo Nicholas Loh, Hayden Anthony Homer   +3 more
doaj   +1 more source

Is It Possible to Expand Oocyte Donors by Decreasing Number of Oocytes for Own Use? Insights From a Large Single-Center Study

Frontiers in Endocrinology, 2021
BackgroundCurrently, in China, only women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles can donate oocytes to others, but at least 15 oocytes must be kept for their own treatment.
Zhiqin Bu, Jiaxin Zhang, Yile Zhang, Yingpu Sun   +3 more
doaj   +1 more source

Oocyte Competence Biomarkers Associated With Oocyte Maturation: A Review

Frontiers in Cell and Developmental Biology, 2021
Oocyte developmental competence is one of the determining factors that influence the outcomes of an IVF cycle regarding the ability of a female gamete to reach maturation, be fertilized, and uphold an embryonic development up until the blastocyst stage ...
Batara Sirait, Batara Sirait, Budi Wiweko, Budi Wiweko, Budi Wiweko, Ahmad Aulia Jusuf, Dein Iftitah, R. Muharam, R. Muharam, R. Muharam   +9 more
doaj   +1 more source

Review: Environment of the ovulatory follicle: modifications and use of biotechnologies to enhance oocyte competence and increase fertility in cattle

Animal, 2023
The oocyte is the basis of life, supporting development from a fertilized cell to an independent multicellular organism. The oocyte’s competence to drive the first cell cycles postfertilization are critical to embryonic survival and subsequent successful
Camila Bortoliero Costa, Trudee Fair, Marcelo M. Seneda   +2 more
doaj   +1 more source

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Nature, 2017
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the ...
Ilya M. Flyamer, Johanna Gassler, Maxim Imakaev, Hugo B. Brandão, S. Ulianov, Nezar Abdennur, S. Razin, L. Mirny, Kikuë Tachibana-Konwalski   +8 more
semanticscholar   +1 more source

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm−oocyte fusion in mice

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance The sperm−oocyte fusion step is important to transport the male genome into oocytes. So far, IZUMO1 and FIMP have been identified as fusion-related proteins in spermatozoa, but the molecular mechanisms underpinning sperm−oocyte fusion and ...
Taichi Noda, Yonggang Lu, Yoshitaka Fujihara, Seiya Oura, Takayuki Koyano, Sumire V. Kobayashi, M. Matzuk, M. Ikawa   +7 more
semanticscholar   +1 more source

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

Nature Communications, 2018
Female meiotic divisions are asymmetric with the formation of large oocytes and small polar bodies, thought to result from cortical spindle placement before anaphase.
Zhe Wei, Jessica Greaney, Chenxi Zhou, Hayden A. Homer   +3 more
doaj   +1 more source

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

PLoS Genetics, 2018
The N6-methyladenosine (m6A) modification is the most prevalent internal RNA modification in eukaryotes. The majority of m6A sites are found in the last exon and 3’ UTRs.
Seth D. Kasowitz, Jun Ma, S. Anderson, N. Leu, Yang Xu, B. Gregory, Richard M Schultz, Richard M Schultz, P. Wang   +8 more
semanticscholar   +1 more source

The influence of timing of oocytes retrieval and embryo transfer on the IVF-ET outcomes in patients having bilateral salpingectomy due to bilateral hydrosalpinx

Frontiers in Surgery, 2023
ObjectiveThe objective of the study was to investigate whether the sequence of oocyte retrieval and salpingectomy for hydrosalpinx affects pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET) patients.Study DesignThere were 1,610 ...
He Yilei, He Yilei, He Yilei, He Yilei, Yang Shuo, Yang Shuo, Yang Shuo, Yang Shuo, Ma Caihong, Ma Caihong, Ma Caihong, Ma Caihong, Yang Yan, Yang Yan, Yang Yan, Yang Yan, Song Xueling, Song Xueling, Song Xueling, Song Xueling, Zhang Jiajia, Zhang Jiajia, Zhang Jiajia, Zhang Jiajia, Liu Ping, Liu Ping, Liu Ping, Liu Ping, Li Rong, Li Rong, Li Rong, Li Rong, Qiao Jie, Qiao Jie, Qiao Jie, Qiao Jie   +35 more
doaj   +1 more source

Histology of the oocytes of Lutjanus peru (Nichols and Murphy, 1922) (Pisces: Lutjanidae)

Ciencias Marinas, 2001
The distinctive characteristics found in each of the development stages of the oocyte in the ovary of Lutjanus peru (Pacific red snapper) are described.
G Lucano-Ramírez, M Villagrán-SantaCruz, S Ruiz-Ramírez, T López-Murillo   +3 more
doaj   +1 more source