Results 21 to 30 of about 264,880 (269)

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

PLoS Genetics, 2018
The N6-methyladenosine (m6A) modification is the most prevalent internal RNA modification in eukaryotes. The majority of m6A sites are found in the last exon and 3’ UTRs.
Seth D. Kasowitz, Jun Ma, S. Anderson, N. Leu, Yang Xu, B. Gregory, R. Schultz, R. Schultz, P. Wang   +8 more
semanticscholar   +1 more source

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm−oocyte fusion in mice

Proceedings of the National Academy of Sciences of the United States of America, 2020
Significance The sperm−oocyte fusion step is important to transport the male genome into oocytes. So far, IZUMO1 and FIMP have been identified as fusion-related proteins in spermatozoa, but the molecular mechanisms underpinning sperm−oocyte fusion and ...
Taichi Noda, Yonggang Lu, Yoshitaka Fujihara, Seiya Oura, Takayuki Koyano, Sumire V. Kobayashi, M. Matzuk, M. Ikawa   +7 more
semanticscholar   +1 more source

Automatic evaluation of human oocyte developmental potential from microscopy images [PDF]

, 2021
Infertility is becoming an issue for an increasing number of couples. The most common solution, in vitro fertilization, requires embryologists to carefully examine light microscopy images of human oocytes to determine their developmental potential. We propose an automatic system to improve the speed, repeatability, and accuracy of this process.
arxiv   +1 more source

Oocyte cryopreservation [PDF]

Human Reproduction, 1998
Cryopreservation of human oocytes has been employed with little success in clinical practice, even though it may solve the legal and ethical problems linked to embryo freezing. Various attempts to cryopreserve human oocytes have mostly been unsuccessful, leading to low oocyte survival rates after thawing, and the search for an optimal protocol for ...
R, Fabbri, E, Porcu, T, Marsella, M R, Primavera, R, Seracchioli, P M, Ciotti, O, Magrini, S, Venturoli, C, Flamigni   +8 more
openaire   +2 more sources

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

Nature, 2017
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the ...
Ilya M. Flyamer, Johanna Gassler, Maxim Imakaev, Hugo B. Brandão, S. Ulianov, Nezar Abdennur, S. Razin, L. Mirny, Kikuë Tachibana-Konwalski   +8 more
semanticscholar   +1 more source

Oocyte maturation [PDF]

Human Reproduction, 1998
Primary oocytes recovered from small and growing follicles of > or = 3 mm in the ovaries of untreated women, can be matured in vitro, will fertilize and develop in vitro, and when transferred to the patient, develop to term. However, the implantation rate of cleaved embryos has been disappointingly low and when embryos are allowed to develop beyond the
A, Trounson, C, Anderiesz, G M, Jones, A, Kausche, N, Lolatgis, C, Wood   +5 more
openaire   +2 more sources

The influence of timing of oocytes retrieval and embryo transfer on the IVF-ET outcomes in patients having bilateral salpingectomy due to bilateral hydrosalpinx

Frontiers in Surgery, 2023
ObjectiveThe objective of the study was to investigate whether the sequence of oocyte retrieval and salpingectomy for hydrosalpinx affects pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET) patients.Study DesignThere were 1,610 ...
He Yilei, He Yilei, He Yilei, He Yilei, Yang Shuo, Yang Shuo, Yang Shuo, Yang Shuo, Ma Caihong, Ma Caihong, Ma Caihong, Ma Caihong, Yang Yan, Yang Yan, Yang Yan, Yang Yan, Song Xueling, Song Xueling, Song Xueling, Song Xueling, Zhang Jiajia, Zhang Jiajia, Zhang Jiajia, Zhang Jiajia, Liu Ping, Liu Ping, Liu Ping, Liu Ping, Li Rong, Li Rong, Li Rong, Li Rong, Qiao Jie, Qiao Jie, Qiao Jie, Qiao Jie   +35 more
doaj   +1 more source

Histology of the oocytes of Lutjanus peru (Nichols and Murphy, 1922) (Pisces: Lutjanidae)

Ciencias Marinas, 2001
The distinctive characteristics found in each of the development stages of the oocyte in the ovary of Lutjanus peru (Pacific red snapper) are described.
G Lucano-Ramírez, M Villagrán-SantaCruz, S Ruiz-Ramírez, T López-Murillo   +3 more
doaj   +1 more source

A Knowledge-Based Decision Support System for In Vitro Fertilization Treatment [PDF]

, 2022
In Vitro Fertilization (IVF) is the most widely used Assisted Reproductive Technology (ART). IVF usually involves controlled ovarian stimulation, oocyte retrieval, fertilization in the laboratory with subsequent embryo transfer. The first two steps correspond with follicular phase of females and ovulation in their menstrual cycle.
arxiv   +1 more source

Impact of Maternal Age on Oocyte and Embryo Competence

Frontiers in Endocrinology, 2018
The overall success of human reproduction, either spontaneously or after IVF, is highly dependent upon maternal age. The main reasons for age-related infertility include reduced ovarian reserve and decreased oocyte/embryo competence due to aging insults,
D. Cimadomo, G. Fabozzi, A. Vaiarelli, N. Ubaldi, F. Ubaldi, L. Rienzi   +5 more
semanticscholar   +1 more source