Results 61 to 70 of about 316,539 (293)
A novel role for DNA methyltransferase 1 in regulating oocyte cytoplasmic maturation in pigs.
PLoS ONE, 2015 Maternal factors are required for oocyte maturation and embryo development. To better understand the role of DNA methyltransferase 1 (Dnmt1) in oocyte maturation and embryo development, small interfering RNA (siRNA) was conducted in porcine oocytes.
Yanjun Huan +4 more
doaj +1 more source
Cyclic nucleotide in oocyte In vitro maturation in Assisted Reproductive Technology
Journal of Biomedicine and Translational Research, 2020 In vitro maturation (IVM) is a promising assisted reproductive technology (ART) for human infertility treatment. However, when cumulus oocyte complexes (COCs) are removed from their follicular environment when manipulated in vitro, it can lead to a ...
Christie L Sun +3 more
doaj +1 more source
Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Bulletin of the National Research Centre, 2023 Background The developmental competence of oocyte derived from in vitro maturation (IVM) is significantly lower than those of oocyte matured in vivo. Rapamycin is an immunosuppressive substance and widely used to prolong the survival and preserve the ...
Hafiza Khatun +3 more
doaj +1 more source
Genomic studies of oocyte physiology reveal mechanisms critical to oocyte competence [PDF]
, 2011 In vitro maturation of porcine oocytes has been intensively studied for many years. However, the in vitro maturation system is still inefficient to produce competent oocytes that can develop to viable embryos.
Yuan, Ye
core
Control of gonad growth, maturation and spawning in teleost fish: A review [PDF]
, 1996 Despite their great variety of reproductive strategies, a general characteristic of most teleosts is that (where known) natural reproduction shows a long-term periodicity, even in tropical habitats (e.g. see contributions in Munro et al.
Lam, Tom J., Munro, Angus D.
core +1 more source
Changes in expression of TNF alpha and its receptors mRNAs in oocytes and granulosa cells in mice with experimental immune ovarian failure [PDF]
, 2014 Purpose: To investigate the expression of TNF- α and its receptors (types I and II) at mRNA level in oocytes and granulose cells as well as to study effect of TNF-α on follicular cell death in mice with experimental immune ovarian failure induced by ...
Grushka, Nataliya +4 more
core +1 more source
Advanced Science, EarlyView.SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source
Journal of Animal Reproduction and Biotechnology, 2018 To determine the differences in the in-vitro ovum maturation process of bovine, we compared the expression of MMPs in these oocytes and cumulus cell throughout oocytes maturated. In an attempt to investigate the effect of MMP activation and inhibitors in
Sang-Hwan Ki, Jong-Taek Yoon
doaj +1 more source
Journal of Ovarian Research, 2020 Purpose Variations in many genes may lead to the occurrence of oocyte maturation defects. To investigate the genetic basis of oocyte maturation defects, we performed clinical and genetic analysis of a pedigree.
Qiong Xing +8 more
doaj +1 more source