Results 1 to 10 of about 298,840 (357)

DNA double strand breaks but not interstrand crosslinks prevent progress through meiosis in fully grown mouse oocytes [PDF]

open access: yes, 2012
There is some interest in how mammalian oocytes respond to different types of DNA damage because of the increasing expectation of fertility preservation in women undergoing chemotherapy.
Julie A. Merriman   +4 more
core   +17 more sources

Eugenol Improves Follicular Survival and Development During in vitro Culture of Goat Ovarian Tissue

open access: yesFrontiers in Veterinary Science, 2022
This study evaluated the effects of different concentrations (10, 20, or 40 μM) of eugenol (EUG 10, EUG 20, or EUG 40), ascorbic acid (50 μg/mL; AA) or anethole (300 μg/mL; ANE 300) on the in-vitro survival and development of goat preantral follicles and
R. F. Silva   +10 more
doaj   +1 more source

Equine ovarian tissue xenografting: impacts of cooling, vitrification, and VEGF

open access: yesReproduction and Fertility, 2021
Ovarian tissue transplantation methods using cooled and cryopreserved samples have been attractive options for fertility preservation in animal models and humans.
Samara Silva Souza   +11 more
doaj   +1 more source

Metformin promotes in vitro maturation of oocytes from aged mice by attenuating mitochondrial oxidative stress via SIRT3-dependent SOD2ac

open access: yesFrontiers in Cell and Developmental Biology, 2022
Human female fecundity decreases irreversibly as chronological age rises, adversely affecting oocyte quality, consequently worsening pregnancy outcomes and increasing the extent of birth defects.
Yongzhi Cao   +49 more
doaj   +1 more source

Oocyte cryopreservation [PDF]

open access: yesHuman Reproduction, 1998
Cryopreservation of human oocytes has been employed with little success in clinical practice, even though it may solve the legal and ethical problems linked to embryo freezing. Various attempts to cryopreserve human oocytes have mostly been unsuccessful, leading to low oocyte survival rates after thawing, and the search for an optimal protocol for ...
R, Fabbri   +8 more
openaire   +2 more sources

Distinct Signaling Pathways Distinguish in vivo From in vitro Growth in Murine Ovarian Follicle Activation and Maturation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Women with cancer and low ovarian reserves face serious challenges in infertility treatment. Ovarian tissue cryopreservation is currently used for such patients to preserve fertility.
Mahboobeh Amoushahi   +3 more
doaj   +1 more source

Dynamic Changes in Proteome during Yak Oocyte Maturation Analyzed Using iTRAQ Technology

open access: yesAnimals, 2023
The aim of this study was to investigate protein regulation at different time points during the in vitro maturation of yak oocytes. Yak oocytes at GV, MI, and MII stages were collected during in vitro maturation, and differential proteomics sequencing ...
Xin Ma   +8 more
doaj   +1 more source

Oocyte maturation [PDF]

open access: yesHuman Reproduction, 1998
Primary oocytes recovered from small and growing follicles of > or = 3 mm in the ovaries of untreated women, can be matured in vitro, will fertilize and develop in vitro, and when transferred to the patient, develop to term. However, the implantation rate of cleaved embryos has been disappointingly low and when embryos are allowed to develop beyond the
A, Trounson   +5 more
openaire   +2 more sources

Genome-wide methylation profile of mitochondrial DNA across bovine preimplantation development

open access: yesEpigenetics, 2023
This study characterized variations in the methylation profile of mitochondrial DNA (mtDNA) during initial bovine embryo development and correlated the presence of methylation with mtDNA transcription.
Camila Bruna de Lima   +3 more
doaj   +1 more source

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