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Programmed mitophagy at the oocyte-to-zygote transition promotes lineage endurance. [PDF]

open access: yesNat Cell Biol
Thendral SB   +7 more
europepmc   +1 more source
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Oocytes

2006
Embryonic stem cells (ESCs), derivatives of totipotential cells of early mammalian embryos, have proven to be one of the most powerful tools for studying developmental and stem cell biology. When injected into embryos, ESCs can contribute to tissues derived from all three germ layers and to the germ line. Prior studies have successfully shown that ESCs
Karin, Hübner   +2 more
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Oocyte attrition

Molecular and Cellular Endocrinology, 2000
During oogenesis, germ cell numbers sharply decrease when meiosis is initiated. There is solid evidence (DNA ladders, in situ detection) that this loss is through apoptosis. Oocyte apoptosis appears to hit mitotic primordial germ cells (PGC), pachytene oocytes and early primordial follicles.
Reynaud, Karine   +1 more
openaire   +3 more sources

Oocyte cryopreservation

Fertility and Sterility, 2006
To review historical and contemporary advances in oocyte-cryopreservation techniques and outcomes.Publications related to oocyte cryopreservation were identified through MEDLINE and other bibliographic databases.Oocyte cryopreservation can be used as an adjunct to conventional IVF and as an option for fertile women to electively cryopreserve their ...
John K, Jain, Richard J, Paulson
openaire   +2 more sources

Oocyte Maturation

Seminars in Reproductive Medicine, 2000
The oocyte is dependent on granulosa cells to provide nutrients and regulatory signals. Granulosa cells must be at the appropriate stage of differentiation to initiate these signals and transmit them to the oocyte. Studies have shown that in vitro-matured oocytes from follicles in early stages of atresia are more competent to support embryonic ...
F L, Barnes, M A, Sirard
openaire   +2 more sources

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