Results 261 to 270 of about 280,910 (369)

Nicotinamide Riboside Supplementation Alleviates Testicular Aging Induced by Disruption of Qprt‐Dependent NAD+ De Novo Synthesis in Mice

Aging Cell, EarlyView.
In Qprt‐deficient mice, testicular NAD+ levels decline accelerated with age, leading to mitochondrial dysfunction, disrupted DSB repair, impaired meiotic sex chromosome inactivation, and germ cell loss. Nicotinamide riboside (NR) supplementation restores NAD+ levels and alleviates these defects, highlighting the importance of NAD+ de novo synthesis in ...
Yining Xu, Huan Wang, Hui Li, Chenlu Wei, Zhenye Zhu, Yanqing Zhao, Jiajia Zhu, Min Lei, Yingpu Sun, Qingling Yang   +9 more
wiley   +1 more source

Nicotinamide riboside supplementation protects against maternal diabetes-associated decline in oocyte quality. [PDF]

Reproduction
Wei C, Zeng X, Wang K, Wang M, Lei M, Zhu Z, Xu Y, Zhao Y, Yang Q, Sun Y.   +9 more
europepmc   +1 more source

FINE STRUCTURE OF THE BOVINE OOCYTE FROM THE MATURE GRAAFIAN FOLLICLE [PDF]

, 1972
W. N. FLEMING, R. G. Saacke
openalex   +1 more source

Negative Effect of Gst‐35 on the Health Span of Caenorhabditis elegans Through Lysosomal Dysfunction via the Pmk‐1 and Skr Genes

Aging Cell, EarlyView.
The overexpression of gst‐35, the mammalian orthologous genes GSTA1, GSTA2, and GSTA3, induces lysosomal dysfunction through the genes pmk‐1 and skr in C. elegans. This overexpression not only promotes an in vivo inflammatory response and accumulation of reactive oxygen species but also significantly shortens the nematode lifespan; inhibits its ...
Yehui Gao, Xinyun Zhang, Congmin Wei, Hongru Lin, Mengchen Wu, Botian Ma, Jinyun Jiang, Shan Li, Hongbing Wang   +8 more
wiley   +1 more source

Successful Clinical Outcome After a Modified Protocol of Rescue In Vitro Maturation of Oocytes: A Case Series Study. [PDF]

Cureus
Petrogiannis N, Filippa M, Chatzovoulou K, Petrogiannis S, Chatzimeletiou K.   +4 more
europepmc   +1 more source

Morphological studies on superovulated rat ova. II. Maturation and time of ovulation of oocytes in adult rats following gonadotrophin treatment

, 1967
Isao Ishibashi
openalex   +2 more sources

Deciphering the Contribution of Circular RNAs to Age‐Related Decline in Sertoli Cell Survivor

Aging Cell, EarlyView.
Sertoli cell survival is regulated by circAbcb9‐ceRNET. Physiologically, the circAbcb9 sponge activity toward miR‐214‐3p ensures the expression of SOX8 and NOTCH2 targets, both crucial in maintaining SC homeostasis. The aging process negatively affects FUS‐dependent backsplicing activity in Sertoli cells leading to circAbcb9 downregulation, and in turn,
Francesco Manfrevola, Nicola Mosca, Vincenza Grazia Mele, Teresa Chioccarelli, Guillaume Martinez, Charles Coutton, Monica Mattia, Mariaceleste Pezzullo, Silvia Fasano, Gilda Cobellis, Nicoletta Potenza, Rosanna Chianese   +11 more
wiley   +1 more source

Nicotinamide mononucleotide biosynthesis and the F-actin cytoskeleton regulate spindle assembly and oocyte maturation quality in post-ovulatory aged porcine oocytes. [PDF]

Cell Commun Signal
Park HJ, Yang SG, Shin JH, Yoon SB, Kim JS, Koo DB.   +5 more
europepmc   +1 more source

Aging‐Associated Vacuolation of Multi‐Ciliated Cells in the Distal Mouse Oviduct Reflects Unique Cell Identity and Luminal Microenvironment

Aging Cell, EarlyView.
Multi‐ciliated cells in the infundibulum and ampulla (INF/AMP) epithelium are vacuolated in aging. Unique cellular susceptibility of the INF/AMP epithelial population and aging‐associated decline in ovarian artery circulation, which supports the ovary and INF/AMP, contribute to this region‐specific vacuolation phenotype, as a consequence of a mildly ...
Keerthana Harwalkar, Nobuko Yamanaka, Alain S. Pacis, Selina Zhao, Katie Teng, Warwick Pitman, Mitaali Taskar, Vera Lynn, Alex Frances Thornton, Matthew J. Ford, Yojiro Yamanaka   +10 more
wiley   +1 more source

Deep Profiling of Oocyte Aging Enabled by Simple One-Step Vial-Based Pretreatment and Single-Cell Proteomics. [PDF]

JACS Au
Zhang H, Zhang H, Huang C, Zeng Q, Tian C, Yang J, He F, Yang Y.   +7 more
europepmc   +1 more source