Open label placebo to treat fatigue in people with multiple sclerosis: feasibility and preliminary effects [PDF]
Pilot and Feasibility StudiesBackground Fatigue is highly prevalent in adults with multiple sclerosis (MS) and current treatments offer limited benefit. It has been speculated that placebos only have an effect when they are administered with deception and concealment, which is ...
Navneet Kaur Baidwan +8 more
doaj +2 more sources
Open-label placebo treatment does not enhance cognitive abilities in healthy volunteers. [PDF]
Sci Rep, 2023 AbstractThe use of so-called ‘smart drugs’ such as modafinil to improve cognitive performance has recently attracted considerable attention. However, their side effects have limited user enthusiasm. Open-label placebo (OLP) treatment, i.e., inert treatments that are openly disclosed to individuals as having no active pharmacological ingredient, has ...
Hartmann H +6 more
europepmc +7 more sources
Deceptive and open-label placebo effects in experimentally induced guilt: a randomized controlled trial in healthy subjects [PDF]
Scientific Reports, 2022 Placebos are known to yield significant effects in many conditions. We examined deceptive and open-label placebo effects on guilt, which is important for self-regulation and a symptom of mental disorders.
Dilan Sezer, Cosima Locher, Jens Gaab
doaj +2 more sources
Open-Label Placebo Interventions With Drinking Water and Their Influence on Perceived Physical and Mental Well-Being [PDF]
Frontiers in Psychology, 2021 In recent years, the postulation that deception is necessary for placebos to have an effect on pain relief or increased well-being has come into question. Latest studies have shown that an openly administered mock drug works just as well as a deceptively
Marco Rathschlag +3 more
doaj +2 more sources
Open-Label Placebo Administration Decreases Pain in Elderly Patients With Symptomatic Knee Osteoarthritis – A Randomized Controlled Trial [PDF]
Frontiers in Psychiatry, 2022 BackgroundRecent studies indicate that the administration of open-label placebos (OLP) can improve symptoms in various medical conditions. The primary aim of this 3-week randomized controlled trial was to examine the effects of OLP treatments on pain ...
Elisabeth Olliges +8 more
doaj +2 more sources
Public and professional attitudes towards deceptive and open-label placebo in functional neurological disorder and wider neurological practice [PDF]
BMJ Neurology OpenBackground Placebo effects are powerful and have been suggested to be particularly relevant in certain neurological conditions, including functional neurological disorder (FND).Methods A survey on attitudes towards and current practice of deceptive ...
Mark J Edwards +2 more
doaj +2 more sources
Why do open-label placebos work? A randomized controlled trial of an open-label placebo induction with and without extended information about the placebo effect in allergic rhinitis. [PDF]
PLoS ONE, 2018 Several studies demonstrated that placebo treatment may have a significant impact on many different symptoms. While in the traditional view concealment of the placebo is essential, recent studies report intriguing evidence that placebos may work even ...
Michael Schaefer +2 more
doaj +4 more sources
Open-Label Placebo Treatment for Acute Postoperative Pain (OLP-POP Study): Study Protocol of a Randomized Controlled Trial [PDF]
Frontiers in Medicine, 2021 Introduction: Open-label placebos have been proposed as way of using long recognized analgesic placebo effects in an ethical manner. Recent evidence shows efficacy of open-label placebos for clinical conditions, but there is need for more research on ...
Dilan Sezer +10 more
doaj +2 more sources
Open label placebo: pill and needle
Integrative Medicine Research, 2020 Dha-Hyun Choi +2 more
doaj +2 more sources
Open-label placebos reduce weight in obesity: a randomized controlled trial
Scientific ReportsObesity is a major public health problem worldwide. Different approaches are known to face this problem, for example, dieting, surgery, or drug interventions. It has also been shown that placebos may help to reduce weight and hunger feelings, but the use
Michael Schaefer +2 more
doaj +3 more sources