Results 31 to 40 of about 16,336,802 (316)

Open-Label Placebo for the Treatment of Cancer-Related Fatigue in Patients with Advanced Cancer: A Randomized Controlled Trial. [PDF]

Oncologist, 2022
Background The purpose of this study was to determine the effects of an open-labeled placebo (OLP) compared to a waitlist control (WL) in reducing cancer-related fatigue (CRF) in patients with advanced cancer using Functional Assessment of Chronic ...
Yennurajalingam S, Azhar A, Lu Z, Rodriguez AJ, Arechiga AB, Guerra-Sanchez M, Stanton P, Andersen CR, Urbauer DL, Bruera E.   +9 more
europepmc   +2 more sources

Open label placebo to treat fatigue in people with multiple sclerosis: feasibility and preliminary effects [PDF]

Pilot and Feasibility Studies
Background Fatigue is highly prevalent in adults with multiple sclerosis (MS) and current treatments offer limited benefit. It has been speculated that placebos only have an effect when they are administered with deception and concealment, which is ...
Navneet Kaur Baidwan, Tracy Tracy, Chia-Ying Chiu, Tanjila Nawshin, Teri Hoenemeyer, Emily Riser, Robert Motl, Kevin Fontaine, Tapan Mehta   +8 more
doaj   +2 more sources

Can an Open-Label Placebo Be as Effective as a Deceptive Placebo? Methodological Considerations of a Study Protocol [PDF]

Medicines, 2020
Background: Placebo has been studied for many years and is ever-present in healthcare. In clinical practice, its use is limited by ethical issues raised by the deception entailed by its administration.
Leo Druart, SaraEve Graham Longsworth, Carole Rolland, Maïa Dolgopoloff, Hugo Terrisse, Jean-Luc Bosson, Nicolas Pinsault   +6 more
doaj   +4 more sources

Open-Label Placebo Interventions With Drinking Water and Their Influence on Perceived Physical and Mental Well-Being

Frontiers in Psychology, 2021
In recent years, the postulation that deception is necessary for placebos to have an effect on pain relief or increased well-being has come into question. Latest studies have shown that an openly administered mock drug works just as well as a deceptively
Marco Rathschlag, Stefanie Klatt, Stefanie Klatt, Stefanie Klatt   +3 more
doaj   +3 more sources

Open label placebo: pill and needle

Integrative Medicine Research, 2020
Dha-Hyun Choi, In-Seon Lee, Younbyoung Chae   +2 more
doaj   +2 more sources

The Role of Patient Beliefs in Open-Label Placebo Effects

Health Psychology, 2019
Objective Recent research on open-label placebos, or placebos administered without deception or concealment, suggests that they can be effective in a variety of conditions.
Kari A. Leibowitz, Emerson J. Hardebeck, J. Parker Goyer, Alia J. Crum   +3 more
semanticscholar   +4 more sources

Open-Label Placebo Treatment for Acute Postoperative Pain (OLP-POP Study): Study Protocol of a Randomized Controlled Trial

Frontiers in Medicine, 2021
Introduction: Open-label placebos have been proposed as way of using long recognized analgesic placebo effects in an ethical manner. Recent evidence shows efficacy of open-label placebos for clinical conditions, but there is need for more research on ...
Dilan Sezer, Matthijs de Leeuw, Cordula Netzer, Markus Dieterle, Andrea Meyer, Sarah Buergler, Cosima Locher, Cosima Locher, Wilhelm Ruppen, Jens Gaab, Tobias Schneider   +10 more
doaj   +3 more sources

Lay perspectives of the open-label placebo rationale: a qualitative study of participants in an experimental trial

BMJ Open, 2021
Objectives To analyse participants’ concepts about the open-label placebo (OLP) effect; to explore their views about the discussion points that are applied in conventional OLP trials and to examine their experiences of taking part in an OLP trial. Design
C. Locher, Sarah Buergler, Antje Frey Nascimento, Linda Kost, C. Blease, J. Gaab   +5 more
semanticscholar   +2 more sources

Methodological considerations for designing and conducting open-label placebo trials. [PDF]

Pain
Hartmann H, Müßgens D, Asan L, Skvortsova A, Kleine-Borgmann J, Schmidt K, Fernandez A, Phalip J, Wessels J, Valerio M, Shedden-Mora M, Bingel U, Aulenkamp JL, Patient Advisory Board of the CRC/TRR 289 Treatment Expectation.   +13 more
europepmc   +2 more sources

More than consent for ethical open-label placebo research

Journal of Medical Ethics, 2020
Recent studies have explored the effectiveness of open-label placebos (OLPs) for a variety of conditions, including chronic pain, cancer-related fatigue and irritable bowel syndrome. OLPs are thought to sidestep traditional ethical worries about placebos
Laura Specker Sullivan
semanticscholar   +3 more sources