Neural underpinnings of open-label placebo effects in emotional distress
Neuropsychopharmacology, 2022 While placebo effects are well-known, research in the last decade revealed intriguing effects that placebos may have beneficial effects even when given without deception.
Mitchell K Schaefer +4 more
semanticscholar +3 more sources
The role of positive information provision in open-label placebo effects.
Applied Psychology: Health and Well-Being, 2023 Open label placebos (OLPs) appear generally efficacious among clinical samples, but the empirical evidence regarding their use in non-clinical and sub-clinical samples, as well as when administered independent of a convincing rationale, is mixed. Healthy
K. Barnes +4 more
semanticscholar +3 more sources
Open label placebo: can honestly prescribed placebos evoke meaningful therapeutic benefits? [PDF]
BMJ, 2018 Results from small clinical trials suggesting that placebos can be ethically and effectively used in clinical practice warrant further study, argue Ted Kaptchuk and Franklin ...
T. Kaptchuk, F. Miller
semanticscholar +4 more sources
Effects of Open-Label Placebos on Visual Food Cue Reactivity in Children and Adolescents [PDF]
ChildrenBackground: A high level of food cue reactivity (FCR) is a risk factor for overeating and weight gain. This randomized trial investigated whether open-label placebos (OLPs: placebos honestly administered) can reduce FCR (reported appetite) in children ...
Anne Schienle +4 more
doaj +2 more sources
Why psychotherapy is an open-label placebo and open-label placebos are psychotherapy [PDF]
, 2023 Abstract In recent years, placebos have undergone a rapid development from methodological chaff to therapeutic wheat. Hereby, the role of placebos as a deceptive control in clinical trials, as well as negative denomination for anything murky, changed to an innovative promise, an effective as well as ethical treatment.
Jens Gaab
openalex +2 more sources
Open-Label-Placebos can reduce pain, but not indigestion during gluten challenge in chronic pain patients [PDF]
Frontiers in PsychologyBackgroundDietary interventions have become a management tool for chronic pain conditions over the past few decades. Certain diets, such as gluten-free diets, are perceived as particularly beneficial by patients, although there is no evidence to support ...
Lena Paschke-Dahl, Regine Klinger
doaj +2 more sources
Effects of open-label placebos and self-monitoring in skin-picking disorder: a randomized crossover trial [PDF]
Frontiers in PsychiatryBackgroundSymptom reduction in skin-picking disorder (SPD) has previously been demonstrated using deceptive placebo treatments. However, to date, no study has investigated the effects of open-label placebos (OLPs) in this context.MethodFifty-two ...
Anne Schienle +2 more
doaj +2 more sources
Placebos without deception: a randomized controlled trial in irritable bowel syndrome. [PDF]
PLoS ONE, 2010 Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception.
Ted J Kaptchuk +9 more
doaj +6 more sources
Prescribing Placebos: An Experimental Examination of the Role of Dose, Expectancies, and Adherence in Open-Label Placebo Effects. [PDF]
Annals of Behavioral Medicine, 2019 Recent evidence indicates that placebo effects can occur even when patients know that they are taking a placebo, termed the open-label placebo effect.To assess whether placebo dose (one pill per day vs. four pills per day), treatment expectancies, and adherence contribute to open-label placebo effects.Healthy undergraduate participants were randomly ...
Jason El Brihi, R. Horne, Kate Faasse
semanticscholar +4 more sources
Scientific Reports, 2023 Three meta-analyses have demonstrated the clinical potential of open-label placebos (OLPs). However, there is a need to synthesize the existing evidence through more complex analyses that would make it possible to answer questions beyond mere efficacy ...
Sarah Buergler +3 more
doaj +2 more sources