Results 31 to 40 of about 156,017 (326)

The role of positive information provision in open‐label placebo effects

Applied Psychology: Health and Well-Being, 2023
Abstract Open label placebos (OLPs) appear generally efficacious among clinical samples, but the empirical evidence regarding their use in non‐clinical and sub‐clinical samples, as well as when administered independent of a convincing rationale, is mixed. Healthy participants ( N
Kirsten Barnes, Emily Babbage, Jessica Barker, Natasha Jain, Kate Faasse   +4 more
openaire   +3 more sources

Open-Label-Placebos can reduce pain, but not indigestion during gluten challenge in chronic pain patients [PDF]

Frontiers in Psychology
BackgroundDietary interventions have become a management tool for chronic pain conditions over the past few decades. Certain diets, such as gluten-free diets, are perceived as particularly beneficial by patients, although there is no evidence to support ...
Lena Paschke-Dahl, Regine Klinger
doaj   +2 more sources

Effects of open-label placebos and self-monitoring in skin-picking disorder: a randomized crossover trial [PDF]

Frontiers in Psychiatry
BackgroundSymptom reduction in skin-picking disorder (SPD) has previously been demonstrated using deceptive placebo treatments. However, to date, no study has investigated the effects of open-label placebos (OLPs) in this context.MethodFifty-two ...
Anne Schienle, Albert Wabnegger, Sandra Tanzmeister   +2 more
doaj   +2 more sources

Reducing Emotional Distress with Open-Label Placebos: Assessing the Role of Motor Engagement in Pill Consumption [PDF]

Behavioral Sciences
It has been posited that ingesting a pill constitutes a pivotal action that facilitates the effects of open-label placebos (OLPs: placebos honestly prescribed).
Anne Schienle, Wolfgang Kogler
doaj   +2 more sources

Placebos in the era of open‐label trials: An update for clinicians [PDF]

European Journal of Clinical Investigation, 2018
AbstractPlacebos have been used extensively by vast numbers of physicians, in a majority of clinical trials. Placebo effects involve behavioural, psychological and genetic factors and have been subject to ethical controversies stemming from the use of deception in treating patients.
Iftach Sagy, Jonathan Abres, Ariel Winnick, Alan Jotkowitz   +3 more
openaire   +3 more sources

Open-label placebo treatment of women with premenstrual syndrome: study protocol of a randomised controlled trial

BMJ Open, 2020
IntroductionRecent evidence suggests that for certain clinical conditions, placebos can improve clinical outcomes even without deception. These so-called open-label placebos (OLPs) bear the advantage of a significant lower risk of adverse events and ...
Cosima Locher, Irving Kirsch, Antje Frey Nascimento, Jens Gaab, Joe Kossowsky, Andrea Meyer   +5 more
doaj   +2 more sources

Neural correlates of expected and perceived treatment efficacy concerning open-label placebos for reducing emotional distress

Brain Research Bulletin
Background: Treatment expectations for open-label placebos (OLPs) - placebos prescribed transparently - refer to what a person anticipates will happen as a result of taking the placebo.
Anne Schienle, Albert Wabnegger
doaj   +2 more sources

Efficacy of open-label placebos for premenstrual syndrome: a randomised controlled trial. [PDF]

BMJ Evid Based Med
ObjectiveTo investigate the efficacy and safety of open-label placebos (OLP) in premenstrual syndrome (PMS).DesignRandomised controlled trial.SettingSwitzerland, 2018–2020.Participants150 women (18–45 years of age) with PMS or premenstrual dysphoric disorder.InterventionRandom assignment (1:1:1) to treatment as usual (TAU), OLP without treatment ...
Frey Nascimento A, Gaab J, Degen B, Rytz M, Holder A, Sezer D, Buergler S, Meyer AH, Kirsch I, Kossowsky J, Locher C.   +10 more
europepmc   +3 more sources

Noble Humbug? Hard and soft laws on clinical placebo use [PDF]

Frontiers in Psychology
Despite the widespread historical and contemporary use of placebos in medicine, legal regulations addressing their administration remain limited in many countries.
Mélina Richard, Mélina Richard, Manuela Ganz, Lena Dominique Hornstein, Bohdan Stehlik, Mélanie Levy, Charlotte R. Blease, Marco Annoni, Bernice S. Elger, Jens Gaab   +9 more
doaj   +2 more sources

Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment

BMJ Open, 2019
Introduction More than 2 million individuals in the USA have an opioid use disorder (OUD). Methadone maintenance treatment is the gold standard of medication-based treatment for OUD, but high-dose methadone is associated with cardiotoxicity and ...
Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca   +15 more
doaj   +2 more sources