Results 101 to 110 of about 811,937 (287)

Longley Building: Reuse and Rehabilitation Feasibility Report [PDF]

open access: yes, 2012
The southern, eastern, and northern façades (the principal façades) have a great amount of decorative masonry including granite, slate coursing, brownstone coursing, and brick veneer (Photo 2). All of these materials are in good condition, except for the
DeBlock, Elizabeth   +6 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Does the Number of Occupants in an Office Influence Individual Perceptions of Comfort and Productivity?—New Evidence from 5000 Office Workers

open access: yesBuildings, 2019
Purpose—The purpose of this article is to present evidence of occupants’ perception of their work environment in five different office types (Solo, Duo, 2–4, 5–8 and 8Plus offices).
Eziaku Onyeizu Rasheed   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Noise and communication: A three-year update

open access: yesNoise and Health, 2012
Noise is omnipresent and impacts us all in many aspects of daily living. Noise can interfere with communication not only in industrial workplaces, but also in other work settings (e.g.
Anthony J Brammer, Chantal Laroche
doaj   +1 more source

Report of the Global Strategy Task Force [PDF]

open access: yes, 2016
The Global Strategy Task Force created a final report documenting its findings and recommendations. The intent of this report is to provide a framework through which the University can articulate and pursue an ambitious set of institutional goals that ...

core  

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Temporal Trajectories in EEG-Based Mental Workload: Effects of Workspace Type

open access: yesBuildings
Open-plan offices are a common format in contemporary work environments, but their exposed nature may increase cognitive demands. Work pods and other enclosed microspaces have been proposed as an alternative.
María Pérez-Martínez   +3 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Comparative studies of offices pre and post — how changing spatial configurations affect organisational behaviours [PDF]

open access: yes, 2009
Understanding the way in which design interventions in an office affect everyday users, and thus shape organisational behaviour, should be high on the agenda for architects, designers and consultants alike. Surprisingly, this seems rarely to be the case.
Budgen, A.   +4 more
core  

Home - About - Disclaimer - Privacy