Results 31 to 40 of about 415,467 (290)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Trust in AI: scale development and validation for online distance learners

BMC Psychology
Trust in artificial intelligence (AI) has emerged as a critical factor influencing students’ interactions with AI-supported learning environments. However, validated instruments for measuring student trust in AI within educational contexts remain limited.
Ayşin Gaye Üstün, Mehmet Yavuz, Bünyami Kayalı, Hasan Uçar, Erdem Erdoğdu, Aras Bozkurt   +5 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Collaborative Approach to OER Policy and Guidelines Development in the Commonwealth: The Case of Botswana, Cameroon, and Sri Lanka

International Review of Research in Open and Distributed Learning, 2018
Access to relevant learning resources is an important aspect in ensuring inclusive and equitable quality education and lifelong learning opportunities for all as outlined in the sustainable development goal 4 (SDG4).
Ishan Sudeera Abeywardena, Shironica P. Karunanayaka, Michael N. Nkwenti, Lekopanye Tladi   +3 more
doaj   +1 more source

PREST in Open and Distance Learning: Brochure [PDF]

, 2005
Informational brochure offering an overview of the Practitioner Research and Evaluation Skills Training (PREST) in Open and Distance Learning training resources.

core  

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Research in Open and Distance Learning

, 2011
Prof. Abtar Kaur, Open University Malaysia in conversation with Prof. Roger Mills, COL Consultant at the Sixth Pan-Commonwealth Forum on Open Learning (PCF6), Kochi, India, November 2010. Video Series on Open and Distance Learning.
Kaur, Abtar, Mills, Roger
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Book Review - Making the move to K–12 online teaching: Research-based strategies and practices

Journal of Open, Flexible and Distance Learning, 2013
Making the move to K–12 online teaching: Research-based strategies and ...
David Adelstein
doaj   +2 more sources

Teaching theology from a distance: Experiences of the Institute of Distance Learning at St Tikhon’s Orthodox University in Moscow, Russia

HTS Teologiese Studies/Theological Studies, 2019
This article considers the basic problem of online education owing to the lack of direct contact between all participants in the study process. The experience of distance theological education in Russia as a whole and the personal experience of two of ...
Gennady Egorov, Tatiana V. Melanina, Jennifer J. Roberts   +2 more
doaj   +1 more source