Results 41 to 50 of about 415,467 (290)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Social Presence and Online Communication: A response to Mersham

Journal of Open, Flexible and Distance Learning, 2011
This article draws upon contemporary social presence theory and research into presence, social presence, and computer-mediated communication to highlight the role of social presence in mitigating the perceived deficiencies in online communication ...
Benjamin Kehrwald
doaj   +2 more sources

Addressing the Learning Needs of Out-of-School Children and Youths through the Expansion of Open Schooling [PDF]

, 2020
At any one time, about 300 million children of school going age are not in school. Experience indicates that when schooling is disrupted, whether by a pandemic, a natural disaster or other reasons, not all children return to the classroom.

core   +1 more source

The Trend in Studies on Decoloniality, Artificial Intelligence and University Classrooms: A Systematic Review of African Higher Education Scholarship

Trends in Higher Education
The convergence of decoloniality, artificial intelligence (AI), and university classroom practice has emerged as a pressing concern in African higher education.
Bunmi Isaiah Omodan, Sindile Amina Ngubane   +1 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Costing distance education and open learning in Sub-Saharan Africa: Working Group on Distance Education and Open Learning [PDF]

, 2004
Both of these "Surveys of policy and practice" were conducted on behalf of COL by the South African Institute for Distance Education (SAIDE) as part of COL's partnership agreement with the Association for the Development of Education in Africa (ADEA ...

core   +1 more source

‘The Big Cough’: Tuberculosis, Popular Perceptions and Beliefs in the Eastern Bechuanaland Protectorate, 1932-1964 [PDF]

Limina: A Journal of Historical and Cultural Studies, 2017
In the 1930s, migrant labour became the prime determinant of emerging infectious diseases, particularly tuberculosis, in the Bechuanaland Protectorate due to the repatriation of infected workers from neighbouring South African mines.
Phuthego Phuthego Molosiwa
doaj  

Learning Management System (LMS) for Academic Inclusion and Learning Agency: An Interpretive Review of Technoprogressivism in ODL Instructional Technology Policy

Journal of Education, Society & Multiculturalism, 2023
Literature frequently describes how ineffective implementation of instructional policy frameworks can make distance learning a lonely and unrewarding academic pursuit, characterized by high student drop-out rates, high failure rates and academic ...
Nkambule Bongani, Ngubane Sindile, Mncube Siphamandla   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Higher Education through Open and Distance Learning

, 1999
Open and distance learning has expanded dramatically in recent years across the world, across the spectrum of subject areas, and across educational levels.

core   +1 more source