Results 91 to 100 of about 26,317,005 (275)

Spatiotemporal variability of chlorophyll-a concentration in the South Brazil Bight using 25 years of multi-sensor orbital data (1998–2022)

Frontiers in Remote Sensing
Chlorophyll-a (Chl-a) concentration is a key climate variable, as its variability is associated with meteorological and oceanographic processes. This study analyzed 25 years (1998–2022) of Chl-a data from the European Space Agency (ESA) Ocean Colour ...
João Felipe Cardoso dos Santos, Milton Kampel, Milton Kampel, Vincent Vantrepotte   +3 more
doaj   +1 more source

Radtools: R utilities for convenient extraction of medical image metadata [version 3; peer review: 2 approved]

F1000Research, 2019
The radiology community has adopted several widely used standards for medical image files, including the popular DICOM (Digital Imaging and Communication in Medicine) and NIfTI (Neuroimaging Informatics Technology Initiative) standards.
Pamela H. Russell, Debashis Ghosh
doaj   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

OA2020: Initiative for the Large-Scale Transformation to Open Access [PDF]

, 2017
Presentation presented by Dr Ralf Schimmer to University of Pretoria staff members in the Merensky 2 auditorium on 10 May 2018.In March 2016, the international initiative Open Access 2020 (OA2020, www.oa2020.org) was launched.
Ralf Schimmer, Schimmer, Ralf
core  

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

TH/TRs–COL11A2 Axis Mediates Loss of a Differentiated Astrocyte State in Hypogyrified Brains

Advanced Science, EarlyView.
Using a gyrencephalic congenital hypothyroidism pig model, this study reveals cerebral atrophy and cortical hypogyrification. Single‐cell sequencing identifies astrocytes as major TH‐responsive cells, with the COL11A2‐enriched Astro‐2 state nearly absent.
Ying Zhang, Xiao Wang, Hongyan Ma, Pengcheng Lyu, Shuangjie Tian, Ruojun Zong, Jiani Chen, Gang Ren, Yongjiang Yang, Zichen Yang, Guosong Qin, Naishi Li, Yanfang Wang, Jianwei Jiao, Jianguo Zhao   +14 more
wiley   +1 more source

Enhancing findability and searchability of research data: Metadata conversion and registration in institutional repositories

Data Science Journal
This paper outlines our practice to enhance the findability and searchability of research data through metadata conversion from the Space Physics Archive Search and Extract (SPASE) schema to a more generic schema, the Japan Consortium for Open Access ...
Masahito Nosé, Atsuki Shinbori, Yoshizumi Miyoshi, Tomoaki Hori, Tsukasa Ohira, Junko Hashiba, Chizuko Naoe, Rui Gakiya, Maiko Okamoto, Takeshi Sagara, Takaaki Aoki, Shigeki Matsubara, Ichiro Takahashi, Hidekazu Hayashi, Kazunari Yamada, Yasuyuki Minamiyama, Yoshimasa Tanaka, Shuji Abe, Satoru UeNo, Shun Imajo, Yasuo Saito, Takuya Ashikita, Yuko Hori, Toshiyuki Shimizu, Nanako Okamura, Kaoru Hirano, Lee Bargatze   +26 more
doaj   +1 more source

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

E-LIS : a step towards redefining Open Access [PDF]

, 2006
The past few years have seen tremendous developments in information production, acquisition, and dissemination. Providing access to information free of charge in electronic formats is a concept that is gaining momentum.
Hirwade, Mangala, Mahajan, Kartika
core   +1 more source