Results 141 to 150 of about 6,217,103 (344)

Socioeconomic status and educational inequality: digital competency pathways to creative problem-solving and academic performance

open access: yesFrontiers in Psychology
IntroductionThe digital divide extends beyond technology access to create educational inequalities through differential competency development, where socioeconomic advantages enable sustained digital engagement that enhances creative problem-solving ...
Jinglu Liu, Yuwei Chen
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Supporting Open Practices with Teachers in Zambia

open access: yesJournal of Learning for Development, 2019
This paper demonstrates how the features and affordances of open learning have been developed in new and productive ways to provide school-based continuing professional development for teachers in Zambia. It presents and critically reviews data from 200
Kris Stutchbury   +2 more
doaj  

Engagement of health and social care employers in professional regulatory fitness to practise – missed regulatory and organisational opportunities?

open access: yesBMC Health Services Research
Background Health and social care professional regulators are organisations that ensure their registrants have the correct qualifications and experience to practise in their profession.
Louise M. Wallace, Mari Greenfield
doaj   +1 more source

A new paradigm for teacher education: supported, open teaching and learning at the Open University

open access: yes, 2006
In this paper we draw on our experience over the last twelve years with three large scale distance education programmes for UK teachers to suggest factors which need to be considered by those embarking on large scale distance learning teacher education ...
Hutchinson, Steven, Wolfenden, Freda
core  

Library and information science publishing : global open access [PDF]

open access: yes, 2005
Brief article describing E-LIS, an open access repository for library and information science material in a range of formats and languages. E-LIS was set up in 2003 with initial funding from the Spanish Ministry of Education, Culture and Sports, in line ...
Brown, Kristina, McCulloch, Emma
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Employer support for health and social care registered professionals, their patients and service users involved in regulatory fitness to practise regulatory proceedings

open access: yesBMC Health Services Research
Background Health and social care employees may be involved in professional regulatory proceedings because their alleged behaviour raises health or conduct concerns.
Louise M Wallace, Mari Greenfield
doaj   +1 more source

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