Results 131 to 140 of about 2,292,987 (304)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Open Education Symposium Panel: Facilitating Openness at the University: Connecting the Opens + Making Change Happen [PDF]
, 2019 This panel discussion begins with brief presentations of several “core open practices”: Open Access, Open Education/Open Educational Resources, and Open Data by experts from the University Libraries at Virginia Tech.
DePauw, Karen P. +7 more
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
How the Sausage Gets Made: Building State-Wide Support for Open Education Initiatives [PDF]
, 2017 Over the last few years, we've seen increasing state-wide support for open education. But how does that support begin? Who's behind those initiatives and what are they doing to advance open education efforts at the state level?
Butterfield, Robert +4 more
core
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Leveraging Open Practices in Scholarship & Teaching in International Liberal Arts Education: What Does Success Look Like? [PDF]
, 2019 Open Access. Open educational resources. Open pedagogy. Beyond access and direct-cost reduction to readers, open educational practices — when deeply understood and thoughtfully implemented — have the potential to transform higher education and to ...
Walz, Anita R.
core
Student Teachers' Perspectives on Academic Support Services in Open and Distance Learning
Journal of Research, Innovation, and Strategies for EducationAcademic support services are crucial for student success in open and distance learning (ODL), particularly in teacher education where learners balance multiple responsibilities.
Nawastheen Fareed Mohamed +4 more
doaj +1 more source