Results 71 to 80 of about 815,523 (315)

Open education resources and higher education academic practice [PDF]

Campus-Wide Information Systems, 2013
PurposeThis paper aims to report on an externally‐funded project and forms part of its dissemination.Design/methodology/approachThe objectives are achieved through a theoretical framing of the project and an alignment of these with the contexts for the project – namely the Professional Standards Framework of the HEA, its use in postgraduate programmes ...
Bradshaw, Peter, Younie, Sarah, Jones, Sarah   +2 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The realities of 'reaching out': enacting the public-facing open scholar role with existing online communities

Journal of Interactive Media in Education, 2013
A core tenet of the open educational resources (OER) movement has long been that 'the world's knowledge is a public good' (Smith & Casserly, 2006, p.2) and should be available for everyone to use, reuse and share.
Leigh-Anne Perryman, Tony Coughlan
doaj   +1 more source

An Open Networking Lab for practical open education [PDF]

, 2019
The Cisco Networking Academy programme (NetAcad) supports education and training in network engineering worldwide. NetAcad works with diverse educational institutions to offer an educational ‘vertical’ from beginner to advanced network engineer. However, as recognised by employment stakeholders, skills shortages in networking remain (Tech Partnership ...
Kear, Karen, Smith, Andrew, Donelan, Helen, Mikroyannidis, Alexander, Jones, Allan, Rosewell, Jonathan, Wermelinger, Michel, Connolly, Teresa, Sanders, Chris, Peasgood, Alice, Williams, Judith, Moss, Nicky, Third, Allan   +12 more
openaire   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Von Open Educational Resources zu Open Educational Practices: der community-geleitete OER-Ansatz der ZHAW Hochschulbibliothek [PDF]

, 2023
Nicole Krüger, Gabriela Lüthi-Esposito
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Extending the Territory: From Open Educational Resources to Open Educational Practices

Journal of Open, Flexible and Distance Learning, 2011
This article examines the findings of the recent OPAL report Beyond OER: Shifting Focus from Resources to Practices. In doing so, it defines current understanding of open educational resources and open educational practices, and highlights the shift from
Ulf-Daniel Ehlers
doaj