Results 51 to 60 of about 20,883,039 (279)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Quali scenari per le pratiche e-learning nell’università? Gli “Open Educational Path”

Lea, 2014
E-learning for over fifteen years has evolved from a simple instrument for virtual educational interactions (1.0) to an environment capable of promoting wide participatory experiences (2.0).
Antonio Calvani Laura Menichetti
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

Open Educational Practices in den Rechtswissenschaften

Bibliothek
Der vorliegende Beitrag stellt die wissenschaftsgeleitete Initiative „OpenRewi“ vor, die in den Rechtswissenschaften durch Open Educational Practices Open Science fördert.
Ramson Lasse, Schneeberger Charlotte, Schulz Katharina   +2 more
doaj   +1 more source

The realities of 'reaching out': enacting the public-facing open scholar role with existing online communities

Journal of Interactive Media in Education, 2013
A core tenet of the open educational resources (OER) movement has long been that 'the world's knowledge is a public good' (Smith & Casserly, 2006, p.2) and should be available for everyone to use, reuse and share.
Leigh-Anne Perryman, Tony Coughlan
doaj   +1 more source

The case for open educational practice [PDF]

Distance Education, 2016
In his recent book The Battle for Open: How Openness Won and Why it Doesn’t Feel Like Victory, Weller (2014) explores why despite the considerable gains made in relation to advocacy, funding and po...
openaire   +1 more source

An Open Networking Lab for practical open education [PDF]

, 2019
The Cisco Networking Academy programme (NetAcad) supports education and training in network engineering worldwide. NetAcad works with diverse educational institutions to offer an educational ‘vertical’ from beginner to advanced network engineer. However, as recognised by employment stakeholders, skills shortages in networking remain (Tech Partnership ...
Kear, Karen, Smith, Andrew, Donelan, Helen, Mikroyannidis, Alexander, Jones, Allan, Rosewell, Jonathan, Wermelinger, Michel, Connolly, Teresa, Sanders, Chris, Peasgood, Alice, Williams, Judith, Moss, Nicky, Third, Allan   +12 more
openaire   +1 more source

Open Educational Resources and their Educational Practices in Higher Education

, 2021
The impact of technology on education in the current context is essential, representing higher education teachers' and students' educational practices. In the present investigation, to achieve the proposed objectives, the netnographic technique implies the interrelation of research techniques, depending on the depth of information raised in the study's
M.Mahendraprabu, Kumar, K.Sathish, M.Mani, P.Saravana Kumar   +3 more
openaire   +2 more sources