Results 91 to 100 of about 252,434 (288)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Open PraxisThis study explores the significance of Open Educational Practices (OEP) in higher education, emphasizing its role in fostering collaboration, diversity, and knowledge sharing.
Abedelaziz Khalil, Brett Bligh
doaj +1 more source
Connecting Open Educational Practices and Open Science
, 2021 Open Education is based on the development, use and reuse of Open Educational Resources (OER). Beyond the basic operations of OER, open educational practices have made it possible to move from resource to instruction. These practices are naturally associated with non-face-to-face education, but, especially after the COVID-19 pandemic, they have also ...
openaire +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Zeitschrift für Hochschulentwicklung, 2013 Der Beitrag knüpft an die vorherrschende sozio-technische Debatte um die freie Zugänglichkeit von digitalen Ressourcen oder Bildungsmaterialien an und erweitert diese hinsichtlich ihrer medienpädagogischen Gehalte, indem ein mediendidaktischer ...
Kerstin Mayrberger, Sandra Hofhues
doaj +1 more source
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Open Educational Practices and Resources : OLCOS Roadmap 2012 [PDF]
, 2007 The Open e-Learning Content Observatory Services (OLCOS) road mapping work was conducted to provide decision makers with an overview of current and likely future developments in Open Educational Resources (OER) and recommendations on how various ...
Rajalakso, Mats +11 more
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FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Quality Assurance in the Open: An Evaluation of OER Repositories [PDF]
, 2013 The World OER Declaration 2012 recommends that States join efforts to facilitate finding, retrieving and sharing OER. The OER movement has thus far spurred the creation of numerous repository initiatives worldwide with the aim of aiding the development ...
Atenas, Javiera +3 more
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