Results 91 to 100 of about 1,704,562 (320)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A Case Study of Teachers’ Open Educational Practices

Je-LKS: Journal of E-Learning and Knowledge Society, 2012
This article presents an exploratory study of the digital practices used by teacher educators regarding Open Educational Resources and Open Educational Practices. Despite the growing diffusion of OER repositories, the results of this research reveal that
Monica Banzato
doaj   +1 more source

A Qualitative Inquiry of K–12 Teachers’ Experience with Open Educational Practices: Perceived Benefits and Barriers of Implementing Open Educational Resources

International Review of Research in Open and Distributed Learning, 2020
Teachers in K–12 schools have shown an increasing desire for open educational resources (OER) to ensure all students can learn effectively. OER provide teachers with free access to open-licensed educational resources that they can retain, reuse, revise ...
Hengtao Tang
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Spectrum Of Open Education Practices

, 2018
Spektrum offener Praktiken in Lehre und Bildung. Werkzeuge passen gegebenenfalls auf mehr als einen Anwendungsfall, sind aber nur einmal gelistet. Rainbow of open practices in teaching and education available as png, pdf, ps, ai & eps for anyone to reuse. Tools may support more than 1 practice, but are listed only once.
Euler, Ellen, Poupart, Raoul
openaire   +1 more source

Go open! Supporting higher education staff engagement in open educational practices [PDF]

, 2021
his paper reports on the activities of a team in Dublin City University (DCU), composed of academic staff and library staff, who engaged in a collaborative project, Go Open, in 2020 and 2021 that encourages members of the DCU community to engage in open educational practices.
Farrell, Orna, Brunton, James, Breen, Ellen, Costello, Eamon, Cox, Ronan, Delaney, Lorraine, Gallagher, Edel, Smyth, Victoria   +7 more
openaire  

Open Science Happens Somewhere: Exploring the use of Science OER in Schools [PDF]

, 2015
This paper concerns a pilot exploring the use of openly licensed content in secondary schools. Specifically it looks at the use of the Open University’s (OU) OpenScienceLab (OSL) in two remote rural schools in the West Highlands of Scotland.
Edwards, D.A., Macintyre, Ronald, Smith, A. J.   +2 more
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

PRAXIS: Open Educational Practices and Open Science to face the challenges of critical Educational Action Research

Open Praxis, 2019
The paper presents the findings from PRAXIS, an educational action research project developed within academic professional learning communities (PLC) in the context of public higher education in Uruguay.
Ada Czerwonogora, Virginia Rodés
doaj   +3 more sources

Open Badges : a best-practice framework [PDF]

, 2016
The widespread adoption of online education is severely challenged by issues of verifiability, reliability, security and credibility. Open Badges exist to address these challenges, but there is no consensus as to what constitutes best practices regarding
Dobson, Simon Andrew, Dow, Lisa, Voogt, Lennert   +2 more
core   +2 more sources