Results 101 to 110 of about 5,756,983 (287)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Digital Transformation as a Catalyst for Sustainability and Open Innovation

Journal of Open Innovation: Technology, Market and Complexity, 2023
G. Robertsone, I. Lapiņa
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Examination of the impact of curiosity and fatigue on brain condition

Scientific Reports
With a growing emphasis on cognitive well-being, this study investigates factors influencing brain health, measured by Fractional Anisotropy Brain Healthcare Quotient (FA-BHQ).
Yan Ni, Keisuke Kokubun, Kiyotaka Nemoto, Yoshinori Yamakawa   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Evolutionary game study of crowdsourcing open innovation synergy mechanism. [PDF]

Heliyon, 2023
Jiang Y, Zhang L, Wu J.
europepmc   +1 more source

Exploring the Role of Organizational Creativity and Open Innovation in Enhancing SMEs Performance

Journal of Open Innovation: Technology, Market and Complexity, 2023
A. Rumanti, A. F. Rizana, Fandi Achmad
semanticscholar   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Teacher practices regarding teaching presence in Vietnamese tertiary online distance education programmes

Humanities & Social Sciences Communications
This study explored how teachers adapt their agentic teaching practices in the context of online distance education programmes in Vietnam. A single-institution case study design was used to collect data through online individual semistructured interviews
Phong Thanh Nguyen, Luan Thanh Nguyen, Vu Mau Nguyen   +2 more
doaj   +1 more source

Evaluation of the Quality Protein and the Effect on Muscle Health of a New Ingredient Based on Hydrolyzed Egg White

Proceedings
Concerns about the growing human population and how to supply future nutritional needs have translated to a growing interest in searching for alternative proteins.
Lidia Tomás-Cobos, Elisa Gallego, Elena Diez-Sánchez, Laura Soriano-Romaní, María Eugenia Juncal-Fernández, Raul da Pereira-Rouco, María Pereda-Legaspi   +6 more
doaj   +1 more source