Results 111 to 120 of about 2,286,604 (339)

Widening the Pool: Open and Inclusive Grant Competitions: Lessons Learned From the Social Innovation Fund [PDF]

, 2012
Offers guidance on implementing transparent and competitive grantmaking processes as required by the Social Innovation Fund, including the benefits of transparency, key design considerations such as clear criteria, and examples of open ...

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Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Fractional Anisotropy of Cingulum Cingulate Mediates the Relationship Between Happiness and Work Performance in Healthy Individuals

Brain and Behavior
Introduction As competition among companies around the world intensifies, the nature of work and the performance required are becoming more complex.
Keisuke Kokubun, Kiyotaka Nemoto, Yoshinori Yamakawa   +2 more
doaj   +1 more source

Evaluation of the Quality Protein and the Effect on Muscle Health of a New Ingredient Based on Hydrolyzed Egg White

Proceedings
Concerns about the growing human population and how to supply future nutritional needs have translated to a growing interest in searching for alternative proteins.
Lidia Tomás-Cobos, Elisa Gallego, Elena Diez-Sánchez, Laura Soriano-Romaní, María Eugenia Juncal-Fernández, Raul da Pereira-Rouco, María Pereda-Legaspi   +6 more
doaj   +1 more source

Innovation brokers and their roles in value chain-network innovation: preliminary findings and a research agenda [PDF]

, 2010
Intervention approaches have been implemented in developing countries to enhance farmer's livelihoods through improving their linkages to markets and inclusiveness in agricultural value chains.
Klerkx, L.W.A., Leeuwis, C., Perez Perdomo, S.A.   +2 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Teacher practices regarding teaching presence in Vietnamese tertiary online distance education programmes

Humanities & Social Sciences Communications
This study explored how teachers adapt their agentic teaching practices in the context of online distance education programmes in Vietnam. A single-institution case study design was used to collect data through online individual semistructured interviews
Phong Thanh Nguyen, Luan Thanh Nguyen, Vu Mau Nguyen   +2 more
doaj   +1 more source

Hydrogen (H₂)/Toluene (TOL) Separation via One and Two Stages of the Bis(triethoxysily)ethane (BTESE) Membranes

Membranes
The separation ability of bis(triethoxysilyl)ethane (BTESE) membranes for hydrogen (H2) purification from hydrogen (H2)/toluene (TOL) gas mixtures after a methylcyclohexane (MCH) dehydrogenation process was investigated via one-stage and two-stage ...
Suhaina Mohd Ibrahim, Xin Yu, Shigeru Miyata, Kengo Mishina, Feridoun Salak, Sulaiman Oladipo Lawal, Toshinori Tsuru, Ken-ichi Sawamura   +7 more
doaj   +1 more source

Green innovation behaviour: Impact of industry 4.0 and open innovation. [PDF]

Heliyon, 2023
Ogiemwonyi O, Alam MN, Hago IE, Azizan NA, Hashim F, Hossain MS.   +5 more
europepmc   +1 more source

Introduction to the open innovation paradigm [PDF]

, 2016
This chapter introduces the teacher and the student to the open innovation paradigm. It points out the rationale for open innovation from the historical point of view and describes the differences between closed and open innovation.
Bašić, M, Dabić, M, Vlajčić, D
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