Results 121 to 130 of about 5,756,983 (287)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Enhancement, brightening and control of radiative emission of dark exciton in WSe2 monolayer by plasmonic effect

npj 2D Materials and Applications
Dark excitons in two-dimensional (2D) transition metal dichalcogenide semiconductors (TMDs) have long radiative lifetimes, making them promising for quantum information and optoelectronics.
Adlen Smiri, F. R. Pratama, Takeshi Nakanishi   +2 more
doaj   +1 more source

Impact of environmental sustainability on open innovation in SMEs: An empirical study considering the moderating effect of gender. [PDF]

Heliyon, 2023
Sarango-Lalangui P, Castillo-Vergara M, Carrasco-Carvajal O, Durendez A.   +3 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Detection of Glutamate Encapsulated in Liposomes by Optical Trapping Raman Spectroscopy

ACS Omega, 2022
Kyoko Masui, Yasunori Nawa, Shunsuke Tokumitsu, Takahiro Nagano, Makoto Kawarai, Hirokazu Tanaka, Tatsuki Hamamoto, Wataru Minoshima, Tomomi Tani, Satoshi Fujita, Hidekazu Ishitobi, Chie Hosokawa, Yasushi Inouye   +12 more
doaj   +1 more source

Multi-disciplinary Perspectives on Citizen Science—Synthesizing Five Paradigms of Citizen Involvement

Citizen Science: Theory and Practice
Research on Open Innovation in Science (OIS) investigates how open and collaborative practices influence the scientific and societal impact of research. Since 2019, the OIS Research Conference has brought together scholars and practitioners from diverse ...
Susanne Beck, Dilek Fraisl, Marion Poetz, Henry Sauermann   +3 more
doaj   +1 more source

Rethinking Open Innovation Beyond the Innovation Funnel [PDF]

Technology Innovation Management Review, 2013
In his article, I first argue that open innovation can be applied in situations where companies do not themselves develop new products or services.
Wim Vanhaverbeke
doaj  

Open innovation: the key to advancing brain health. [PDF]

CNS Spectr, 2023
Eyre HA, Searfoss J, Hopwood M, Berk M, Chen S, Cummings J, Veron F, Zikopoulou V, Ibanez A, Kelly K, Soares JC, Smith E, Gilbert BJ.   +12 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source