Results 71 to 80 of about 1,007,234 (319)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Open Method of Coordination in the European Union: A Trojan Horse – But who is the rider?
There seems to be another spectre in Europe, this time it has a little bit of a hydra. The original name was «governance», seemingly a new born child, supposedly the successor of «governing». The parents seem to be a large E, standing for Europe and a
Peter Herrmann
doaj +2 more sources
DEVELOPMENTAL STAGES OF THE EDUCATIONAL STRATEGY OF THE EUROPEAN UNION
The article is dedicated to the analysis of the evolution of the educational strategy of EU in the process of its development aimed at the economic stability and security in the region.
Olena I. Lokshyna
doaj
The Open method of coordination in European Education and Training Policy: New forms of integration through soft policy-making [PDF]
New forms of governance, such as the Open Method of Coordination have become more and more popular within European policy-making. This paper discusses an example of the Open Method of Coordination (OMC) under-analysed so far by the literature, namely the
Drachenberg, Ralf
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Evolvement of Public Open Spaces in Historical Environments of Yerevan City
In this article the role of public open spaces in Yerevan city as well as their correct and literate organisation from an architectural and planning perspective are studied and evaluated.
Mamyan Zaruhi +2 more
doaj +1 more source
UNESCO'S MISSION IN THE DEVELOPMENT OF TRANSNATIONAL HIGHER EDUCATION
The article is devoted to the characterization of the constitutive influence of UNESCO on the transnational higher education formation at the end of the XX - the beginning of the XXI century, in particu-lar, to substantiate strategies for its development
Наталія Авшенюк
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

