Results 31 to 40 of about 159,413 (329)
Coupling of Open Reading Frames by Translational Bypassing
Annual Review of Biochemistry, 2000 ▪ Abstract Translational bypassing joins the information found within two disparate open reading frames into a single polypeptide chain. The underlying mechanism centers on the decoding properties of peptidyl-transfer RNA (tRNA) and involves three ...
John F. Atkins +2 more
core +3 more sources
Open Reading Frame Phylogenetic Analysis on the Cloud [PDF]
International Journal of Genomics, 2013 Phylogenetic analysis has become essential in researching the evolutionary relationships between viruses. These relationships are depicted on phylogenetic trees, in which viruses are grouped based on sequence similarity.
Che-Lun Hung, Chun-Yuan Lin
doaj +3 more sources
Translational Control via Protein-Regulated Upstream Open Reading Frames
Cell, 2011 SummaryAnalysis of the regulation of msl-2 mRNA by Sex lethal (SXL), which is critical for dosage compensation in Drosophila, has uncovered a mode of translational control based on common 5′ untranslated region elements, upstream open reading frames ...
Jan Medenbach +2 more
exaly +2 more sources
Translation of Overlapping Open Reading Frames Promoted by Type 2 IRESs in Avian Calicivirus Genomes. [PDF]
VirusesArhab Y, Pestova TV, Hellen CUT.
europepmc +2 more sources
Proteogenomic Discovery of Novel Open Reading Frames With HLA Immune Presentation on Human β-Cells [PDF]
DiabetesNeelanjan Mukherjee +2 more
exaly +2 more sources
Microbiology Spectrum, 2023 Short open reading frames (sORF) have the potential to encode small proteins, sORF-encoded peptides (SEP), which are less than or equal to 100 amino acids in length.
Jerome Genth +5 more
doaj +1 more source
Non-conventional peptides in plants: From gene regulation to crop improvement
Crop Journal, 2023 Conventional peptides (CPs) and non-conventional peptides (NCPs) are generated from small open reading frames, but most CPs are derived from large precursors. NCPs, which are derived from sequences other than conventional open reading frames or annotated
Huan Chen, Jingjuan Yu, Wen-Xue Li
doaj +1 more source
Coupled protein synthesis and ribosome-guided piRNA processing on mRNAs
Nature Communications, 2021 Ribosome can mediate piRNA biogenesis from long non-coding RNAs following translation of the short open reading frames. Here the authors show that 80S ribosome also guides piRNA production from 3’ UTR of protein-coding genes after translation of long ...
Yu H. Sun +9 more
doaj +1 more source
Standardized annotation of translated open reading frames. [PDF]
Nat Biotechnol, 2022 Ribosome profiling (Ribo-seq) has extended our understanding of the translational ‘vocabulary’ of the human genome, uncovering thousands of open reading frames (ORFs) within long noncoding RNAs (lncRNAs) and presumed untranslated regions (UTRs) of protein-coding genes.
Mudge JM +34 more
europepmc +8 more sources
OpenVar: functional annotation of variants in non-canonical open reading frames
Cell & Bioscience, 2022 Background Recent technological advances have revealed thousands of functional open reading frames (ORF) that have eluded reference genome annotations. These overlooked ORFs are found throughout the genome, in any reading frame of transcripts, mature or ...
Marie A. Brunet +2 more
doaj +1 more source