Results 41 to 50 of about 162,248 (282)

Recurrent differential expression of open reading frames on chromosome 14 in human metastatic breast cancer. [PDF]

open access: yes, 2021
Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). We leveraged the power of systems-level comparative transcriptome analysis in human tissues to discover genes associated with brain metastasis in human breast cancer by ...
Shahan Mamoor
core   +1 more source

OpenVar: functional annotation of variants in non-canonical open reading frames

open access: yesCell & Bioscience, 2022
Background Recent technological advances have revealed thousands of functional open reading frames (ORF) that have eluded reference genome annotations. These overlooked ORFs are found throughout the genome, in any reading frame of transcripts, mature or ...
Marie A. Brunet   +2 more
doaj   +1 more source

Selecting Open Reading Frames From DNA [PDF]

open access: yesGenome Research, 2003
We describe a method to select DNA encoding functional open reading frames (ORFs) from noncoding DNA within the context of a specific vector. Phage display has been used as an example, but any system requiring DNA encoding protein fragments, for example, the yeast two-hybrid system, could be used.
Zacchi P.   +4 more
openaire   +4 more sources

Almespar: An Open Reading Frames Detection Tool Using Python [PDF]

open access: yes, 2023
Background and aims. Open reading frames (ORFs) are sections of a reading frame that do not include any stop codons. A reading frame is a sequence of nucleotide triplets read as codons indicating amino acids; a single strand of DNA has three potential ...
Osamah Alrouwab1,2 * , Ismail Mallian1, Buthaynah Ramadhan2, Kareemah Abdullah2, Omiema Aznad2, Abd Almajid Abu khashim3, Mahmoud Gargotti4
core   +1 more source

The mitochondrial genome of Cavia aperea

open access: yesMitochondrial DNA. Part B. Resources, 2020
Cavia aperea is a wild guinea pig found throughout South America. The previously published mitochondrial sequence for C. aperea was highly divergent from the C. porcellus sequence and contained stop codons within open reading frames.
Azizia Wahedi   +3 more
doaj   +1 more source

Open reading frame cloning: identification, cloning, and expression of open reading frame DNA. [PDF]

open access: yesProceedings of the National Academy of Sciences, 1982
A plasmid was constructed that facilitates the cloning and expression of open reading frame DNA. A DNA fragment containing a bacterial promoter and the amino terminus of the cI gene of bacteriophage lambda was fused to an amino-terminally deleted version of the lacZ gene.
M R, Gray   +3 more
openaire   +2 more sources

A Novel Mutation in the Upstream Open Reading Frame of the CDKN1B Gene Causes a MEN4 Phenotype [PDF]

open access: yes, 2013
PubMed ID: 23555276This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
OCCHI, GIANLUCA   +79 more
core   +1 more source

Open Reading Frames Analysis. [PDF]

open access: yes, 2016
The Bridger assembly produced the most amount of open reading frames for sequences with >799 bps (red), >999 bps (blue), and >1,199 bps (green).
Carolyn S. Bentivegna (2602489)   +4 more
core   +1 more source

Predicting functional upstream open reading frames in Saccharomyces cerevisiae

open access: yesBMC Bioinformatics, 2009
Background Some upstream open reading frames (uORFs) regulate gene expression (i.e., they are functional) and can play key roles in keeping organisms healthy. However, how uORFs are involved in gene regulation is not yet fully understood. In order to get
Kristiansson Erik   +5 more
doaj   +1 more source

Open reading frames of unknown function. [PDF]

open access: yes, 2013
Open reading frames of unknown function.
Andreas Mayer (187816)   +1 more
core   +1 more source

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