Results 71 to 80 of about 780,027 (226)

A comprehensive catalog of predicted functional upstream open reading frames in humans

open access: yesNucleic Acids Research, 2018
Upstream open reading frames (uORFs) latent in mRNA transcripts are thought to modify translation of coding sequences by altering ribosome activity. Not all uORFs are thought to be active in such a process.
Patrick D. McGillivray   +5 more
semanticscholar   +1 more source

Characterization and expression analysis of Staphylococcus aureus pathogenicity island 3 - Implications for the evolution of staphylococcal pathogenicity islands [PDF]

open access: yes, 2002
We describe the complete sequence of the 15.9-kb staphylococcal pathogenicity island 3 encoding staphylococcal enterotoxin serotypes B, K, and Q. The island, which meets the generally accepted definition of pathogenicity islands, contains 24 open reading
Kapur, Vivek   +5 more
core  

eIF1 modulates the recognition of suboptimal translation initiation sites and steers gene expression via uORFs [PDF]

open access: yes, 2017
Alternative translation initiation mechanisms such as leaky scanning and reinitiation potentiate the polycistronic nature of human transcripts. By allowing for reprogrammed translation, these mechanisms can mediate biological responses to stimuli.
Fijalkowska, Daria   +5 more
core   +1 more source

John Pier, Configurazioni narrative

open access: yesEnthymema, 2009
The article moves in the direction of an intertextual narratology integrating semiotic reflection with logic, focusing on the concept of “configuration” as model of comprehension (Mink, Ricoeur).
Alessandra Diazzi
doaj   +1 more source

Characterization of a second open reading frame in genome segment 10 of bluetongue virus [PDF]

open access: yes, 2015
Viruses have often evolved overlapping reading frames in order to maximise their coding capacity. Until recently, the segmented double-stranded (ds) RNA genome of viruses of the Orbivirus genus was thought to be monocistronic but the identification of ...
Barry, Gerald   +11 more
core   +2 more sources

Proteomic Detection and Validation of Translated Small Open Reading Frames

open access: yesCurrent Protocols in Chemical Biology, 2019
Small open reading frames (smORFs) encode previously unannotated polypeptides or short proteins that regulate translation in cis (eukaryotes) and/or are independently functional (prokaryotes and eukaryotes).
Alexandra Khitun, Sarah A. Slavoff
semanticscholar   +1 more source

An approach to pathway reconstruction using whole genome metabolic models and sensitive sequence searching

open access: yesJournal of Integrative Bioinformatics, 2009
Metabolic models have the potential to impact on genome annotation and on the interpretation of gene expression and other high throughput genome data. The genome of Streptomyces coelicolor genome has been sequenced and some 30% of the open reading frames
Saqi Mansoor   +4 more
doaj   +2 more sources

Structural-Functional Analysis of Cryptic Plasmids in Yersinia pestis Strains from Two Natural Plague Foci of Russia

open access: yesПроблемы особо опасных инфекций, 2015
Identified are the complete nucleotide sequences of two cryptic plasmids - pCKF from the Central-Caucasian high-mountain plague focus and pTP33 - from Tuva mountain plague focus in Russia. It is established that the size of the pCKF is 5.4 kbp, and its G-
E. G. Oglodin   +6 more
doaj   +1 more source

Genome sequence of the Bacteroides fragilis phage ATCC 51477-B1 [PDF]

open access: yes, 2008
The genome of a fecal pollution indicator phage, Bacteroides fragilis ATCC 51477-B1, was sequenced and consisted of 44,929 bases with a G+C content of 38.7%.
Shawn A Hawkins   +4 more
core   +3 more sources

Simultaneous cloning of open reading frames into several different expression vectors

open access: yesBioTechniques, 2003
Genomic sequencing has enabled the prediction of thousands of genes, most of which either cannot be assigned a function or can be only broadly categorized on the basis of sequence alone.
Clement A. Stanyon   +2 more
doaj   +1 more source

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