Results 91 to 100 of about 45,040 (267)

Multiple Machine Learning as a Powerful Tool for Star Cluster Analysis

open access: yesThe Astronomical Journal
This work proposes a multiple machine learning method (MMLM) aiming to improve the accuracy and robustness of the analysis of star clusters. The MMLM performance is evaluated by applying it to the reanalysis of an old binary cluster candidate—comprised ...
Denilso Camargo
doaj   +1 more source

Spectrophotometry of 237 Stars in 7 Open Clusters

open access: yesThe Astronomical Journal, 1997
23 pages, LaTex (aaspp4), 6 tables, 4 in .tex mode; 2 as ADC-format data tables with their own readme file; 16 figures.
Clampitt, Lori, Burstein, David
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Disk-locking Regulates Stellar Rotation in Young Clusters: Insights from NGC 2264

open access: yesThe Astrophysical Journal
Many young clusters possess extended main sequences, a phenomenon commonly ascribed to stellar rotation. However, the mechanism behind their very wide stellar rotation distributions remains unclear.
Yutian Bu   +3 more
doaj   +1 more source

Symbiotic stars in Galactic open clusters

open access: yes
17 pages, 3 figures, accepted for publication in ...
Kueß, Lukas, Paunzen, Ernst
openaire   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A Comprehensive Study of Open Cluster Chemical Homogeneity Using APOGEE and Milky Way Mapper Abundances

open access: yesThe Astrophysical Journal
Stars in an open cluster are assumed to have formed from a broadly homogeneous distribution of gas, implying that they should be chemically homogeneous.
Amaya Sinha   +6 more
doaj   +1 more source

Flare Stars as Age Indicators in Open Clusters [PDF]

open access: yesSymposium - International Astronomical Union, 1990
A new set of isochrones derived from overshooting evolutionary models, allows one to give a homogeneous age determination for open clusters with solar chemical composition and in a range of age 4 107 ÷ 1.5 109 yr. In this context is derived an empirical new age calibration - absolute magnitude of the supposed brightest flare star in a cluster versus ...
openaire   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy