Results 91 to 100 of about 16,650,235 (304)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Kinematical distances to open star clusters [PDF]
, 1988 Kinematical distances are estimated for six open star clusters. They agree fairly well with the photometric distances. The kinematical distances cannot, at present, be estimated better than the photometric distances.
Ram Sagar,, Bhatt, Harish C.
core +2 more sources
PSR J1922+37: a 1.9 s Pulsar Discovered in the Direction of the Old Open Cluster NGC 6791
The Astrophysical Journal LettersMore than 300 pulsars have been discovered in Galactic globular clusters; however, none have been found in open clusters. Here we present results from a 20 hr survey of seven open clusters with the Five-hundred-meter Aperture Spherical radio Telescope ...
Xiao-Jin Liu +10 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Revisiting Open Clusters within 200 pc in the Solar Neighborhood with Gaia DR3
The Astronomical JournalIn this study, we develop a membership identification method and apply it for 30 open clusters (OCs) within 200 pc of the Sun using astrometric data of Gaia DR3.
Penghui Liu +5 more
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Open star clusters in the Milky Way
, 2017 Context. The global survey of star clusters in the Milky Way (MWSC) is a comprehensive list of 3061 objects that provides, among other parameters, distances to clusters based on isochrone fitting.
Siegfried Röser +7 more
core +1 more source
The Astrophysical JournalAge-benchmark brown dwarf and planetary-mass-object spectroscopy is key to characterizing substellar evolution. In this paper, we present the JHK medium-resolution ( R ∼ 3000) spectra of 25 7–76 M _Jup (spectral types L3.0–M6.0) brown dwarfs and ...
Elena Manjavacas +5 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Forest Fire Clustering: A Novel Tool for Identifying Star Members of Clusters
The Astronomical JournalIn the era of a data-driven landscape, the development of an efficient and interpretable method has become a pivotal tool for robustly identifying memberships of clusters.
Xingyin Wei +8 more
doaj +1 more source