Results 101 to 110 of about 137,348 (307)

Velocity Dispersion of the Open Cluster NGC 2571 by Radial Velocities and Proper Motions

open access: yesThe Astronomical Journal
We use a kernel density estimator method to evaluate the stellar velocity dispersion in the open cluster NGC 2571. We derive the 3D velocity dispersion using both proper motions as extracted from Gaia Data Release 3 and single-epoch radial velocities as ...
Maxim V. Kulesh   +5 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Ultracool dwarfs in open clusters and star-forming regions

open access: yesEPJ Web of Conferences, 2013
In this contribution I review the results of the UKIRT Infrared Deep Sky Survey (UKIDSS) Galactic Clusters Survey (GCS) on the Initial Mass Function (IMF) and the current searches for young T dwarfs in open clusters and star-forming regions.
Lodieu Nicolas
doaj   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Probing the Nature of Rotation in the Pleiades, Alpha Persei, and Hyades Clusters

open access: yesThe Astrophysical Journal
Unraveling the internal kinematics of open clusters is crucial for understanding their formation and evolution. However, there is a dearth of research on this topic, primarily due to the lack of high-quality kinematic data.
C. J. Hao   +7 more
doaj   +1 more source

A multiwavelength study of star formation in the very young open cluster NGC 6530 [PDF]

open access: bronze, 1997
M. E. van den Ancker   +5 more
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Double Compact Binary Merger Rate Density in Open Star Clusters: Black Holes, Neutron Stars, and White Dwarfs

open access: yesThe Astrophysical Journal
Studying compact object binary mergers in star clusters is crucial for understanding stellar evolution and dynamical interactions in galaxies. Open clusters in particular are more abundant over cosmic time than globular clusters.
Savannah Cary   +3 more
doaj   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

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