Results 51 to 60 of about 5,322,488 (334)

TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation

FEBS Letters, EarlyView.
TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling, Kodi Hunter, Celest W. S. Tay, Nicola T. Wood, Philip Cohen   +4 more
wiley   +1 more source

Goodbye flat lymphoma biology

FEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria, Cèlia Dobaño‐López, Patricia Pérez‐Galán, Christine Bezombes   +3 more
wiley   +1 more source

LCC-HVDC Converter Station Reactive Power Optimization and Two-Layer Coordination Strategy Research Based on Synchronous Sondenser

南方能源建设, 2023
[Introduction] Under the existing converter station reactive power compensation scheme, the synchronous condenser only provides transient reactive power support, and the AC (Alternating Current) filter undertakes steady-state reactive power compensation ...
Dongqing ZHANG, Lingling XU, Yanlong LI, Guohua ZHANG   +3 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Aerodynamic uplift force improvement in single-strip high-speed pantograph via key parameter regulation with mechanism investigation

Theoretical and Applied Mechanics Letters
This study addresses the significant disparity in aerodynamic uplift forces experienced by single-strip high-speed pantographs under different operating directions.
Yafeng Zou, Xianghong Xu, Rui Zhou, Zichen Liu, Liming Lin   +4 more
doaj   +1 more source

Problems of organization of operating conditions of large heat supply systems and their solutions based on multilevel modeling†

E3S Web of Conferences, 2018
The paper unveils relevance of applying the methodology of multi-level modeling of thermal-hydraulic conditions of heat supply systems (HSS) and the software which are realized in the informationcomputing system “ANGARA-TS”, which make possible ...
Shalaginiva Zoya I., Tokarev Vyacheslav V.   +1 more
doaj   +1 more source

Emotional intelligence and British expatriates’ cross-cultural adjustment in international construction projects

, 2016
Today’s internationalized business demands global mindset, intercultural sensitivity and the ability to skilfully negotiate through cross-cultural interactions. Therefore, the overall aim was to investigate the influence of emotional intelligence (EI) on
Ashwini Konanahalli, Lukumon O. Oyedele
semanticscholar   +1 more source

The multidrug and toxin extrusion (MATE) transporter DTX51 antagonizes non‐cell‐autonomous HLS1–AMP1 signaling in a region‐specific manner

FEBS Letters, EarlyView.
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Operating temperature adjusted constraint layers

Acta Acustica, 2006
Elastic epoxy resin systems show a high loss factor around the glass transition temperature. A series of temperature adjusted epoxy resins are shown to have excellent performance in constraint layer type of vibration dampling systems.
Aalto, Samu, Saarinen, Kari, Lindroos, Tomi, Lamula, Lasse   +3 more
openaire   +2 more sources