Results 91 to 100 of about 300,033 (304)
Evaluation of Horizontal Curve Radius Effect on Driving Speed in Two Lane Rural Road. Pilot Study
The Baltic Journal of Road and Bridge Engineering, 2020 This paper presents a case study of driving speed at horizontal curves in the regional road. The literature review of operating speed at horizontal curves in regional roads expresses the difference between design speed and driving speed.
Mindaugas Šeporaitis +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Effect of radii of exemption on ground delay programs with operating cost based cruise speed reduction [PDF]
, 2013 When a ground delay program (GDP) is defined, a radius of exemption is typically set to exclude from having to realize ground delay aircraft departing from greater distances than the selected radius distance. A trade-off exists when defining this radius:
Delgado, L., Prats, X.
core
Operating System Support for High-Speed Communication [PDF]
, 1996 This paper looks at the I/O bottleneck in operating systems, with particular focus on high-speed networking. We start by identifying the causes of this bottleneck, which are rooted in a mismatch of operating system behavior with the performance ...
Peter Druschel
core +1 more source
Predicting Operating Speeds of Passenger Cars on Single-Carriageway Road Tangents
InfrastructuresThis research addresses the challenge of predicting operating vehicles’ speeds (V85) on single-carriageway road tangents. While most previous models rely on preceding segment speeds or focus on curves, this research develops an independent prediction ...
Juraj Leonard Vertlberg +3 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Operating system support for high-speed networking. [PDF]
, 1994 The advent of high-speed networks may soon increase the network bandwidth available to workstation class computers by two orders of magnitude. Combined with the dramatic increase in microprocessor speed, these technological advances make possible new ...
Druschel, Peter
core
The Analysis of Impacting Urban Expressway Operating Speed Factors [PDF]
, 2011 With many large cities accelerating the pace of urban expressway construction, at the same time it has to be thought-provoking which factors is related with the urban expressway operating speed?
Hong Wang, Zhang Ming Jiang
core +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source