Results 81 to 90 of about 1,235,898 (307)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Recherches en Éducation, 2016 This paper aims to understand the design of training in occupational risk prevention with cross-references to ergonomics and professional didactics. A case study realized in the delivery of ready-to-use concrete domain is presented.
Christine Vidal-Gomel
doaj +1 more source
The role of linked data and the semantic web in building operation [PDF]
, 2013 Effective Decision Support Systems (DSS) for building service managers require adequate performance data from many building data silos in order to deliver a complete view of building performance. Current performance analysis techniques tend to focus on a
Coakley, Daniel +4 more
core +1 more source
Automated Game Design Learning
, 2017 While general game playing is an active field of research, the learning of game design has tended to be either a secondary goal of such research or it has been solely the domain of humans.
Mateas, Michael +2 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A survey of simulation techniques in commerce and defence [PDF]
, 2008 Despite the developments in Modelling and Simulation (M&S) tools and techniques over the past years, there has been a gap in the M&S research and practice in healthcare on developing a toolkit to assist the modellers and simulation practitioners with ...
Eldabi, T +5 more
core
Comparator Design in Sensors for Environmental Monitoring [PDF]
, 2018 This paper presents circuit design considerations of comparator in analog-to-digital converters (ADC) applied for a portable, low-cost and high performance nano-sensor chip which can be applied to detect the airborne magnetite pollution nano particulate ...
Fan, Hua +4 more
core +1 more source
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Architecture and Information Requirements to Assess and Predict Flight Safety Risks During Highly Autonomous Urban Flight Operations [PDF]
As aviation adopts new and increasingly complex operational paradigms, vehicle types, and technologies to broaden airspace capability and efficiency, maintaining a safe system will require recognition and timely mitigation of new safety issues as they ...
Ancel, Ersin +15 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source