Results 121 to 130 of about 602,372 (317)

An Integrated Assessment Framework for Water Resources Management: A DSS Tool and a Pilot Study Application [PDF]

Decision making for the management of water resources is a complex and difficult task. This is due to the complex socio-economic system that involves a large number of interest groups pursuing multiple and conflicting objectives, within an often ...
Anita Fassio, Carlo Giupponi, Jaroslaw Mysiak   +2 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

The impact of public lighting improvement on crimes and incivilities reduction in Chile

Frontiers in Sociology
The objective of this study is to evaluate the impact of the Public Lighting Replacement Programme on crimes and incivilities reduction in various municipalities in Chile. A quantitative approach was employed, using stratification and matching techniques
Pablo Cadena-Urzúa, Javier Guardiola, Francisco Montes   +2 more
doaj   +1 more source

Configuration of robust manufacturing systems [PDF]

, 2013
Considering the increasing turbulence in the markets, many companies are faced with the task of responding to changes in customer demand in a flexible and timely manner.
Heinicke, Matthias
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Operatives training programmes in India

, 1966
During the last few years great changes have taken place in the fishing industry as a result of which production of fish in the world has increased enormously. From an insignificant trade employing tools and methods of primitive nature, fishing in many countries has become an important industry utilizing complex modern vessels equipped with electronic ...
openaire   +3 more sources

Evaluation of the impact of public support from the point of convergence criterion

Littera Scripta, 2016
The article deals with the ex post evaluation of the impact of drawing funds from operational programmes to achieve convergence in the field of tourism after the Czech Republic became a member of the EU.
Lucie Sobotková, Martin Sobotka
doaj  

Indicators calculated for Competitiveness Operational Programme

International Journal of Academic Research in Accounting, Finance and Management Sciences, 2015
The objective of this presentation consists in combining theoretical notions concerning the OP Competitiveness, its role with a practical study on the method of calculation of the indicators in order to adopt optimal bankable projects. The benchmark performance must be based on net benefits technique that takes into account the differences between ...
openaire   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source