Results 231 to 240 of about 602,372 (317)

Restoring the core acute medical unit (AMU) function - a quality improvement initiative from a district general hospital. [PDF]

Future Healthc J
Wijewardane A, Dyer P.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Constructing the Corpus of Children's Video Media (CCVM): A new resource and guidelines for constructing comparable and reusable corpora. [PDF]

Behav Res Methods
Gowenlock A, Rodd J, Malory B, Norbury C.   +3 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Diabetes Alters microRNA Expression in Epicardial and Subcutaneous Adipose Tissue from Patients Undergoing Elective Cardiac Surgery. [PDF]

Cells
Santos D, Canotilho A, Coutinho G, Prieto D, Antunes P, Antunes M, Moreira AFL, Falcão-Pires I, Carvalho E, Dalgaard LT.   +9 more
europepmc   +1 more source

ANNEXES to the REPORT FROM THE COMMISSION TO THE EUROPEAN PARLIAMENT, THE COUNCIL AND THE EUROPEAN COURT OF AUDITORS 2015 Annual Management and Performance Report for the EU Budget. COM (2016) 446 final, ANNEXES 1 to 6, 5.7.2016 [PDF]

, 2016

core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

TB preventive therapy: uptake and time to initiation during implementation of ‘7-1-7’

IJTLD Open
A.D. Harries, D. Nair, P. Thekkur, R. Ananthakrishnan, R. Thiagesan, J.M. Chakaya, I. Mbithi, B. Jamil, R. Fatima, M. Khogali, R. Zachariah, S.D. Berger, S. Satyanarayana, A.M.V. Kumar, A.F. Bochner, A. McClelland   +15 more
doaj   +1 more source

Improved Antibiotic Prescribing for Acute Conjunctivitis After Operational Research: A Before-and-After Study in a Ghanaian Eye Hospital. [PDF]

Trop Med Infect Dis
Ansong HK, Nair D, Koomson JA, Amponsah OKO, Acquah JF, Buckman J, Ramsay A, Hope PKF.   +7 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source