Results 121 to 130 of about 2,075,471 (240)

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Correlation over Decomposed Signals: A Non-Linear Approach to Fast and Effective Sequences Comparison [PDF]

open access: yesarXiv, 2000
A novel non-linear approach to fast and effective comparison of sequences is presented, compared to the traditional cross-correlation operator, and illustrated with respect to DNA sequences.
arxiv  

Kinetic equation for a gas with attractive forces as a functional equation

open access: yesAnnales Universitatis Paedagogicae Cracoviensis: Studia Mathematica, 2009
Diffusion problems studied in the time scale comparable with time of particles collision lead to kinetic equations which for step-wise potentials are functional equations in the velocity space.
Ryszard Wojnar
doaj  

Solution of Some Boundary Value Problems Including Nonlinear Fractional Differential Equations

open access: yesپژوهش‌های ریاضی, 2020
Introduction In this paper, by mixed monotone operators and their fixed points, we investigate the existence and uniqueness of positive solution for the following boundary value problems via nonlinear fractional differential equations.   and   where  
Hojjat Afshari, Mojtaba Sajjadmanesh
doaj  

Potential application of thermography (IRT) in animal production and for animal welfare. A case report of working dogs

open access: yesAnnali dell'Istituto Superiore di Sanità, 2014
INTRODUCTION. The authors describe the thermography technique in animal production and in veterinary medicine applications. The thermographic technique lends itself to countless applications in biology, thanks to its characteristics of versatility, lack ...
Veronica Redaelli   +5 more
doaj   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Some Remarks on Some Strongly Coupled Reaction-Diffusion Equations [PDF]

open access: yesarXiv, 2003
The primary goal of this paper is to characterize solutions to coupled reaction-diffusion systems. Indeed, we use operators theory to show that under suitable assumptions, then the solutions to the reaction-diffusion equations exist. As applications, we consider a mathematical model arising in Biology and in Chemistry.
arxiv  

Collective Bionic Algorithm with Biogeography Based Migration Operator for Binary Optimization

open access: yes, 2016
Received 26.11.2015, received in revised form 30.12.2015, accepted 25.01.2016 The meta-heuristic called Co-Operation of Biology Related Algorithms (COBRA) developed earlier for solving real-valued optimization problems has also been modified for solving ...
S. Akhmedova   +3 more
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

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