Results 111 to 120 of about 3,216,975 (364)

DRONE OPERATORS – LEGAL RESPONSIBILITY [PDF]

open access: yesChallenges of the Knowledge Society, 2016
Drones or unmanned or remote vehicles represent a new generation of devices that were designed to help mankind achieve better results in areas that were proven to hazardous.
Andrei-Alexandru STOICA
doaj  

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Operator Symbols and Operator Indices [PDF]

open access: yesSymmetry, 2019
We suggest a certain variant of symbolic calculus for special classes of linear bounded operators acting in Banach spaces. According to the calculus we formulate an index theorem and give applications to elliptic pseudo-differential operators on smooth manifolds with non-smooth boundaries.
openaire   +2 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Fundamental Properties of Interval‐Valued Pythagorean Fuzzy Aggregation Operators

open access: yesInternational Journal of Intelligent Systems, 2016
In this paper, we investigate the multiple attribute group decision making (MAGDM) problems with interval‐valued Pythagorean fuzzy sets (IVPFSs). First, the concept, operational laws, score function, and accuracy function of IVPFSs are defined.
Xindong Peng, Yong Yang
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Wasserstein-Based Evolutionary Operators for Optimizing Sets of Points: Application to Wind-Farm Layout Design

open access: yesApplied Sciences
This paper introduces an evolutionary algorithm for objective functions defined over clouds of points of varying sizes. Such design variables are modeled as uniform discrete measures with finite support and the crossover and mutation operators of the ...
Babacar Sow   +4 more
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

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